Zebrafish pancreas development

被引：81
作者：
Tiso, Natascia [1 ]
Moro, Enrico [1 ]
Argenton, Francesco [1 ]
机构：
[1] Univ Padua, Dipartimento Biol, I-35121 Padua, Italy
来源：
MOLECULAR AND CELLULAR ENDOCRINOLOGY | 2009年 / 312卷 / 1-2期
关键词：
Zebrafish; Pancreas; Development; Morphogenesis; Patterning; Differentiation; Regeneration; HORMONE-EXPRESSING CELLS; ENDODERM FORMATION; MULTIPLE ROLES; JAGGED GENES; BETA-CELLS; IN-VIVO; SPECIFICATION; ENDOCRINE; ISLET; LIVER;
D O I：
10.1016/j.mce.2009.04.018
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
An accurate understanding of the molecular events governing pancreas development can have an impact on clinical medicine related to diabetes, obesity and pancreatic cancer, diseases with a high impact in public health. Until 1996, the main animal models in which pancreas formation and differentiation could be studied were mouse and, for some instances related to early development, chicken and Xenopus. Zebrafish has penetrated this field very rapidly offering a new model of investigation, by joining functional aenomics, genetics and in vivo whole mount visualization, Danio rerio has allowed large scale and fine multidimensional analysis of gene functions during pancreas formation and differentiation. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：24 / 30
页数：7
相关论文
共 72 条
[1]   Morpholino knock-down of Antivin1 and Antivin2 upregulates nodal signaling [J].
Agathon, A ;
Thisse, B ;
Thisse, C .
GENESIS, 2001, 30 (03) :178-182
[2]   casanova plays an early and essential role in endoderm formation in zebrafish [J].
Alexander, J ;
Rothenberg, M ;
Henry, GL ;
Stainier, DYR .
DEVELOPMENTAL BIOLOGY, 1999, 215 (02) :343-357
[3]   Regulation of nodal signalling and mesendoderm formation by TARAM-A, a TGFβ-related type I receptor [J].
Aoki, TO ;
Mathieu, J ;
Saint-Etienne, L ;
Rebagliati, MR ;
Peyriéras, N ;
Rosa, FM .
DEVELOPMENTAL BIOLOGY, 2002, 241 (02) :273-288
[4]  
Aoki TO, 2002, DEVELOPMENT, V129, P275
[5]   Delta-mediated specification of midline cell fates in zebrafish embryos [J].
Appel, B ;
Fritz, A ;
Westerfield, M ;
Grunwald, DJ ;
Eisen, JS ;
Riley, BB .
CURRENT BIOLOGY, 1999, 9 (05) :247-256
[6]  
Argenton F, 1996, MOL CELL BIOL, V16, P1714
[7]   Early appearance of pancreatic hormone-expressing cells in the zebrafish embryo [J].
Argenton, F ;
Zecchin, E ;
Bortolussi, M .
MECHANISMS OF DEVELOPMENT, 1999, 87 (1-2) :217-221
[8]   Functional characterization of the trout insulin promoter: Implications for fish as a favorable model of pancreas development [J].
Argenton, F ;
Walker, MD ;
Colombo, L ;
Bortolussi, M .
FEBS LETTERS, 1997, 407 (02) :191-196
[9]   Notch signaling: Cell fate control and signal integration in development [J].
Artavanis-Tsakonas, S ;
Rand, MD ;
Lake, RJ .
SCIENCE, 1999, 284 (5415) :770-776
[10]   Pancreas development in zebrafish: Early dispersed appearance of endocrine hormone expressing cells and their convergence to form the definitive islet [J].
Biemar, F ;
Argenton, F ;
Schmidtke, R ;
Epperlein, S ;
Peers, B ;
Driever, W .
DEVELOPMENTAL BIOLOGY, 2001, 230 (02) :189-203
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