Bioinorganic Life and Neural Activity: Toward a Chemistry of Consciousness?

被引:39
作者
Chang, Christopher J. [1 ,2 ,3 ]
机构
[1] Univ Calif Berkeley, Dept Chem, Howard Hughes Med Inst, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Helen Wills Neurosci Inst, Berkeley, CA 94720 USA
[3] Lawrence Berkeley Natl Lab, Div Chem Sci, Berkeley, CA 94720 USA
关键词
FLUORESCENT SENSORS; NEURODEGENERATIVE DISEASES; BIOLOGICAL-SYSTEMS; IMAGING METALS; LIVING SYSTEMS; COPPER; INDICATORS; CALCIUM; PROBES; NEUROBIOLOGY;
D O I
10.1021/acs.accounts.6b00531
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Identifying what elements are required for neural activity as potential path toward consciousness, which represents life with the state or quality of awareness, is a "Holy Grail" of chemistry. As life itself arises from coordinated interactions between elements across the periodic table, the majority of which are metals, new approaches for analysis, binding, and control of these primary chemical entities can help enrich our understanding of inorganic chemistry in living systems in a context that is both universal and personal.
引用
收藏
页码:535 / 538
页数:4
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