Prediction, clinical characteristics and prognosis of intracerebral hemorrhage in hepatocellular carcinoma patients with intracerebral metastasis

被引：29

作者：

Hsieh, Mei-Jen ^{[1
]}

Lu, Cheng-Hsien ^{[1
]}

Tsai, Nai-Wen ^{[1
]}

Lui, Chun-Chung ^{[2
]}

Chuang, Yao-Chung ^{[1
]}

Huang, Chi-Ren ^{[1
]}

Chen, Shu-Fang ^{[1
]}

Chang, Chiung-Chih ^{[1
]}

Chang, Hsueh-Wen ^{[3
]}

Chang, Wen-Neng ^{[1
]}

机构：

[1] Chang Gung Univ, Coll Med, Chang Gung Mem Hosp, Kaohsiung Med Ctr,Dept Neurol, Niao Sung Hsiang, Kaohsiung Hsien, Taiwan

[2] Chang Gung Univ, Coll Med, Chang Gung Mem Hosp, Kaohsiung Med Ctr,Dept Radiol, Kaohsiung, Taiwan

[3] Natl Sun Yat Sen Univ, Dept Biol Sci, Kaohsiung 80424, Taiwan

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2009年 / 16卷 / 03期

关键词：

Clinical characteristics; Hepatocellular carcinoma; Intracerebral hemorrhage; Intracerebral metastasis; Predicting factors; Prognostic factors; NERVOUS-SYSTEM INVOLVEMENT; ACUTE EPIDURAL HEMATOMA; HEPATITIS-B-VIRUS; EXTRAHEPATIC METASTASES; RISK-FACTORS; GEOGRAPHIC VARIATIONS; DIAGNOSIS; PREVALENCE; RESECTION; CANCER;

D O I：

10.1016/j.jocn.2008.05.010

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The clinical characteristics of intracerebral hemorrhage (ICH) in hepatocellular carcinoma (HCC) patients with intracerebral metastasis (IcM) have not been reported on extensively. We compared the clinical characteristics between patients with ICH (w-ICH, 18 patients) and without ICH (wo-ICH, 24 patients) in HCC patients with IcM. Using multivariate logistic regression, only habitual alcohol consumption is a significant predictor of ICH in HCC patients with IcM (adjusted odds ratio [OR] = 4.7, 95% CI = 1.2617.71, p = 0.022). Patients with ICH also had lower Glasgow Coma Scale scores at the time of admission (p = 0.032) and lower incidence of infratentorial metastasis (p = 0.014). Using correlation analysis, only blood platelet count on admission was positively correlated with survival duration after the diagnosis of IcM in the wo-ICH group (p = 0.000) but not in the w-ICH group. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：394 / 398

页数：5

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