The New Kid on the Block: RET in Lung Cancer

被引：21

作者：

Gainor, Justin F. ^{[1
]}

Shaw, Alice T. ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USA

来源：

CANCER DISCOVERY | 2013年 / 3卷 / 06期

关键词：

FUSIONS; IDENTIFICATION; GENE; ADENOCARCINOMA; MUTATIONS; GEFITINIB; KIF5B-RET; ALK;

D O I：

10.1158/2159-8290.CD-13-0174

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

RET has recently been identified as a potential new oncogenic driver in a subset of patients with non-small cell lung cancer (NSCLC). In this issue of Cancer Discovery, Drilon and colleagues report preliminary trial data with a RET inhibitor in RET fusion-positive NSCLC, validating RET as a therapeutic target in lung cancer.

引用

页码：604 / 606

页数：3

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