Dietary Intake of Carotenoids and Their Antioxidant and Anti-Inflammatory Effects in Cardiovascular Care

被引:205
作者
Ciccone, Marco Matteo [1 ]
Cortese, Francesca [1 ]
Gesualdo, Michele [1 ]
Carbonara, Santa [1 ]
Zito, Annapaola [1 ]
Ricci, Gabriella [1 ]
De Pascalis, Francesca [1 ]
Scicchitano, Pietro [1 ]
Riccioni, Graziano [2 ]
机构
[1] Univ Bari, Dept Emergency & Organ Transplantat DETO, Cardiovasc Dis Sect, I-70124 Bari, Italy
[2] San Camillo Lellis Hosp, Intens Cardiol Care Unit, I-71043 Manfredonia, Italy
关键词
CORONARY-HEART-DISEASE; LOW-DENSITY-LIPOPROTEIN; ACUTE MYOCARDIAL-INFARCTION; ARTERY RISK DEVELOPMENT; SERUM BETA-CAROTENE; OXIDATIVE STRESS; VITAMIN-C; PLASMA CAROTENOIDS; ALPHA-TOCOPHEROL; HAEMATOCOCCUS ASTAXANTHIN;
D O I
10.1155/2013/782137
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Cardiovascular disease related to atherosclerosis represents nowadays the largest cause of morbidity and mortality in developed countries. Due to inflammatory nature of atherosclerosis, several studies had been conducted in order to search for substances with anti-inflammatory activity on arterial walls, able to exert beneficial roles on health. Researches investigated the role of dietary carotenoids supplementation on cardiovascular disease, due to their free radicals scavenger properties and their skills in improving low-density lipoprotein cholesterol resistance to oxidation. Nevertheless, literature data are conflicting: although some studies found a positive relationship between carotenoids supplementation and cardiovascular risk reduction, others did not find any positive effects or even prooxidant actions. This paper aimed at defining the role of carotenoids supplementation on cardiovascular risk profile by reviewing literature data, paying attention to those carotenoids more present in our diet (beta-carotene, alpha-carotene, beta-cryptoxanthin, lycopene, lutein, zeaxanthin, and astaxanthin).
引用
收藏
页数:11
相关论文
共 101 条
[1]   Anti-Atherosclerotic Molecules Targeting Oxidative Stress and Inflammation [J].
Adameova, A. ;
Xu, Y. J. ;
Duhamel, T. A. ;
Tappia, P. S. ;
Shan, L. ;
Dhalla, N. S. .
CURRENT PHARMACEUTICAL DESIGN, 2009, 15 (27) :3094-3107
[2]   Tomato lycopene and low density lipoprotein oxidation: A human dietary intervention study [J].
Agarwal, S ;
Rao, AV .
LIPIDS, 1998, 33 (10) :981-984
[3]   Plasma carotenoids and onset of dysglycemia in an elderly population - Results of the Epidemiology of Vascular Ageing Study [J].
Akbaraly, Tasnime N. ;
Fontbonne, Annick ;
Favier, Alain ;
Berr, Claudine .
DIABETES CARE, 2008, 31 (07) :1355-1359
[4]   Oxidative stress and its role in the pathogenesis of ischaemic stroke [J].
Allen, C. L. ;
Bayraktutan, U. .
INTERNATIONAL JOURNAL OF STROKE, 2009, 4 (06) :461-470
[5]   Relation of consumption of vitamin E, vitamin C, and carotenoids to risk for stroke among men in the United States [J].
Ascherio, A ;
Rimm, EB ;
Hernán, MA ;
Giovannucci, E ;
Kawachi, I ;
Stampfer, MJ ;
Willett, WC .
ANNALS OF INTERNAL MEDICINE, 1999, 130 (12) :963-970
[6]   Smoking cessation and cardiovascular disease risk factors: Results from the Third National Health and Nutrition Examination Survey [J].
Bakhru, A ;
Erlinger, TP .
PLOS MEDICINE, 2005, 2 (06) :528-536
[7]   ATHEROSCLEROSIS - BASIC MECHANISMS - OXIDATION, INFLAMMATION, AND GENETICS [J].
BERLINER, JA ;
NAVAB, M ;
FOGELMAN, AM ;
FRANK, JS ;
DEMER, LL ;
EDWARDS, PA ;
WATSON, AD ;
LUSIS, AJ .
CIRCULATION, 1995, 91 (09) :2488-2496
[8]   Quantitative assessment of antioxidant properties of natural colorants and phytochemicals:: carotenoids, flavonoids, phenols and indigoids.: The role of ß-carotene in antioxidant functions [J].
Beutner, S ;
Bloedorn, B ;
Frixel, S ;
Blanco, IH ;
Hoffmann, T ;
Martin, HD ;
Mayer, B ;
Noack, P ;
Ruck, C ;
Schmidt, M ;
Schülke, I ;
Sell, S ;
Ernst, H ;
Haremza, S ;
Seybold, G ;
Sies, H ;
Stahl, W ;
Walsh, R .
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2001, 81 (06) :559-568
[9]   The role of vitamin E (tocopherol) supplementation in the prevention of stroke A meta-analysis of 13 randomised controlled trials [J].
Bin, Qiong ;
Hu, Xueying ;
Cao, Yunfei ;
Gao, Feng .
THROMBOSIS AND HAEMOSTASIS, 2011, 105 (04) :579-585
[10]   Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases [J].
Bjelakovic, G. ;
Nikolova, D. ;
Ll, Gluud ;
Simonetti, R. G. ;
Gluud, C. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2008, (02)