Risk of thromboembolism after cerebral venous thrombosis

被引:11
作者
Maqueda, VM [1 ]
Thijs, V [1 ]
机构
[1] Univ Hosp Leuven, Dept Neurol, Louvain, Belgium
关键词
cerebral venous thrombosis; stroke;
D O I
10.1111/j.1468-1331.2006.01211.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The outcome of cerebral venous thrombosis (CVT) has been studied infrequently. We assessed the frequency of recurrence of cerebral or systemic thromboembolism and factors influencing recurrence. We performed a retrospective study of consecutive patients with CVT in the period 1985-2002 who were admitted to the University Hospital Gasthuisberg. We performed a chart review and a semi-standardized telephone interview that focused on recurrent CVT or systemic thromboembolism. Fifty-four CVT patients with a mean age of 42 years were followed up for a mean of 3.5 years. Eighty percent were women. Coagulation disorders were found in 17 patients (31%). One patient (1.9%) had recurrent CVT and seven patients (12.9%) suffered systemic thromboembolism after a median of 2.5 months. Patients with recurrent thromboembolism more often had coagulopathies (P = 0.04) or a history of deep venous thrombosis (P = 0.007). Patients with early recurrent venous thromboembolism often were not treated with oral anticoagulants (P < 0.001). It was evident from the above study that a substantial number of patients suffer recurrent thromboembolism after CVT.
引用
收藏
页码:302 / 305
页数:4
相关论文
共 8 条
[1]   Incidence of recurrent venous thromboembolism in relation to clinical and thrombophilic risk factors: prospective cohort study [J].
Baglin, T ;
Luddington, R ;
Brown, K ;
Baglin, C .
LANCET, 2003, 362 (9383) :523-526
[2]   Cerebral venous thrombosis: diagnosis and management [J].
Bousser, MG .
JOURNAL OF NEUROLOGY, 2000, 247 (04) :252-258
[3]   Cerebral venous thrombosis -: 3-year clinical outcome in 55 consecutive patients [J].
Breteau, G ;
Mounier-Vehier, F ;
Godefroy, O ;
Gauvrit, JY ;
Mackowiak-Cordoliani, MA ;
Girot, M ;
Bertheloot, D ;
Hénon, H ;
Lucas, C ;
Leclerc, X ;
Fourrier, F ;
Pruvo, JP ;
Leys, D .
JOURNAL OF NEUROLOGY, 2003, 250 (01) :29-35
[4]   Antithrombotic therapy for venous thromboembolic disease [J].
Büller, HR ;
Agnelli, G ;
Hull, RD ;
Hyers, TA ;
Prins, AH ;
Raskob, GE .
CHEST, 2004, 126 (03) :401S-428S
[5]   Prognosis of cerebral vein and dural sinus thrombosis - Results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) [J].
Ferro, JM ;
Canhao, P ;
Stam, J ;
Bousser, MG ;
Barinagarrementeria, F .
STROKE, 2004, 35 (03) :664-670
[6]   Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism [J].
Kearon, C ;
Ginsberg, JS ;
Kovacs, MJ ;
Anderson, DR ;
Wells, P ;
Julian, JA ;
MacKinnon, B ;
Weitz, JI ;
Crowther, MA ;
Dolan, S ;
Turpie, AG ;
Geerts, W ;
Solymoss, S ;
van Nguyen, P ;
Demers, C ;
Kahn, SR ;
Kassis, J ;
Rodger, M ;
Hambleton, J ;
Gent, M .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (07) :631-639
[7]   Long-term prognosis in cerebral venous thrombosis - Follow-up of 77 patients [J].
Preter, M ;
Tzourio, C ;
Ameri, A ;
Bousser, MG .
STROKE, 1996, 27 (02) :243-246
[8]   Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism [J].
Ridker, PM ;
Goldhaber, SZ ;
Danielson, E ;
Rosenberg, Y ;
Eby, CS ;
Deitcher, SR ;
Cushman, M ;
Moll, S ;
Kessler, CM ;
Elliott, CG ;
Paulson, R ;
Wong, T ;
Bauer, KA ;
Schwartz, BA ;
Miletich, JP ;
Bounameaux, H ;
Glynn, RJ ;
Ridker, PM ;
Glynn, RJ ;
Danielson, EM ;
Bates, D ;
Christen, W ;
DeFonce, P ;
Griffin, W ;
Jackson, F ;
Murray, A ;
Taylor, K ;
Johnson, K ;
McKenna, K ;
Pierre, J ;
Holman, B ;
Dessources, F ;
Quinn, P ;
Laurinaitis, T ;
MacFadyen, J ;
Eby, C ;
Miletich, JP ;
Porche-Sorbet, R ;
Goldhaber, SZ ;
Morrison, RB ;
MacDougall, RC ;
Morrison, RM ;
Lamas, G ;
Bailey, K ;
Gersh, B ;
Pellegrino, E ;
Rick, M ;
Vaughan, D ;
Rosenberg, Y ;
Goldhaber, SZ .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (15) :1425-1434