New Constituents from the Korean Sponge Plakortis simplex

被引：5

作者：

Oh, Jung Soon ^{[1
]}

Hwang, Buyng Su ^{[1
]}

Kang, Ok-Hwa ^{[2
,3
]}

Kwon, Dong-Yeul ^{[2
,3
]}

Rho, Jung-Rae ^{[1
]}

机构：

[1] Kunsan Natl Univ, Dept Oceanog, Jeonbuk 573701, South Korea

[2] Wonkwang Univ, Inst Biotechnol, Coll Pharm, Jeonbuk 570749, South Korea

[3] Wonkwang Univ, Inst Biotechnol, Wonkwang Oriental Med Res Inst, Jeonbuk 570749, South Korea

来源：

MARINE DRUGS | 2013年 / 11卷 / 11期

基金：

新加坡国家研究基金会;

关键词：

Plakortis simplex; cyclic peroxide; cyclic peroxyketal; pyridinium; NMR; OKINAWAN MARINE SPONGE; CYCLIC PEROXIDES; INDONESIAN SPONGE; FATTY-ACIDS; A-C; HALICHONDRIOIDES; METABOLITES; MANADOPEROXIDES; ALKALOIDS;

D O I：

10.3390/md11114407

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Six new cyclic peroxides (1-6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1-6 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.

引用

页码：4407 / 4418

页数：12

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