The relationship between lingual and hypoglossal nerve function and quality of life in head and neck cancer

被引:22
作者
Elfring, T. [6 ]
Boliek, C. A. [2 ]
Winget, M. [3 ,4 ]
Paulsen, C. [3 ]
Seikaly, H. [1 ,5 ,6 ]
Rieger, J. M. [1 ,2 ]
机构
[1] Santa Barbara Cty Educ Off, Santa Maria, CA USA
[2] Univ Alberta, Fac Rehabil Med, Dept Speech Pathol & Audiol, Edmonton, AB T6G 2G4, Canada
[3] Univ Alberta, Sch Publ Hlth, Edmonton, AB T6G 2G4, Canada
[4] Alberta Hlth Serv, Edmonton, AB, Canada
[5] Univ Alberta, Fac Med & Dent, Div Otolaryngol Head & Neck Surg, Edmonton, AB T6G 2G4, Canada
[6] Misericordia Community Hosp, Inst Reconstruct Sci Med, Edmonton, AB, Canada
基金
加拿大健康研究院;
关键词
head and neck neoplasms; quality of life; sensation; lingual nerve transection; hypoglossal nerve; deglutition; OROPHARYNGEAL CANCER; SWALLOWING FUNCTION; PHARYNGEAL CANCER; FREE-FLAP; RECONSTRUCTION; OUTCOMES; SURGERY; SPEECH; TONGUE; RADIOTHERAPY;
D O I
10.1111/joor.12116
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Sensorimotor impairment of the tongue has the potential to affect speech and swallowing. The purpose of this study was to critically examine the effects of nerve preservation and reinnervation after reconstruction of the base of tongue on patient-perceived outcomes of quality of life (QoL) related to speech and swallowing through completion of the EORTC QLQ-H&N35 stan-dardised questionnaire. Thirty participants with a diagnosis of base of tongue cancer underwent primary resection and reconstruction with a radial forearm free flap, which may or may not have included nerve repair to the lingual nerve, hypoglossal nerve or both. Eight QoL domains sensitive to changes in motor and sensory nerve function were included in the analysis. Transected lingual and hypoglossal nerves were associated with difficulty in swallowing, social eating, dry mouth and social contact. There were fewer problems reported when these nerves were either repaired or left intact. There were no significant differences between patient nerve status and QoL outcomes for speech, sticky saliva and use of feeding tubes. This study was the first to examine the impact of sensory or motor nerve transection and reconstruction on health-related QoL outcomes.
引用
收藏
页码:133 / 140
页数:8
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