An endophytic Taxol-producing fungus BT2 isolated from Taxus chinensis var. mairei

被引：0

作者：

Guo, BH

Wang, YC

Zhou, XW

Hu, K

Tan, F

Miao, ZQ

Tang, KX ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Fudan SJTU Nottingham Plant Biotechnol R&D Ctr, Shanghai Key Lab Agrobiotechnol, Plant Biotechnol Res Ctr,Sch Agr & Biol, Shanghai 200030, Peoples R China

[2] SW Normal Univ, Sch Life Sci & Technol, Chongqing 400715, Peoples R China

[3] Fudan Univ, Fudan SJTU Nottingham Plant Biotechnol R&D Ctr, State Key Lab Genet Engn, Sch Life Sci,Morgan Tan Int Ctr Life Sci, Shanghai 200433, Peoples R China

来源：

AFRICAN JOURNAL OF BIOTECHNOLOGY | 2006年 / 5卷 / 10期

关键词：

baccatin III; endophytic fungus; Taxol; Taxus chinensis var. mairei;

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

BT2, a newly isolated endophytic fungus from Taxus chinensis var. mairei, was observed to produce Taxol. Besides Taxol, a potent anticancer drug, BT2 could also yield taxane baccatin III, which was an important intermediate for Taxol and semi-synthesis of Taxol in industry. The isolation of such a fungus may provide a promising alterative approach to produce Taxol, and BT2 can serve as a potential material for fungus engineering to improve Taxol production.

引用

页码：875 / 877

页数：3

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