An endophytic Taxol-producing fungus BT2 isolated from Taxus chinensis var. mairei

被引：0
|
作者：
Guo, BH
Wang, YC
Zhou, XW
Hu, K
Tan, F
Miao, ZQ
Tang, KX [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Fudan SJTU Nottingham Plant Biotechnol R&D Ctr, Shanghai Key Lab Agrobiotechnol, Plant Biotechnol Res Ctr,Sch Agr & Biol, Shanghai 200030, Peoples R China
[2] SW Normal Univ, Sch Life Sci & Technol, Chongqing 400715, Peoples R China
[3] Fudan Univ, Fudan SJTU Nottingham Plant Biotechnol R&D Ctr, State Key Lab Genet Engn, Sch Life Sci,Morgan Tan Int Ctr Life Sci, Shanghai 200433, Peoples R China
来源：
AFRICAN JOURNAL OF BIOTECHNOLOGY | 2006年 / 5卷 / 10期
关键词：
baccatin III; endophytic fungus; Taxol; Taxus chinensis var. mairei;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
BT2, a newly isolated endophytic fungus from Taxus chinensis var. mairei, was observed to produce Taxol. Besides Taxol, a potent anticancer drug, BT2 could also yield taxane baccatin III, which was an important intermediate for Taxol and semi-synthesis of Taxol in industry. The isolation of such a fungus may provide a promising alterative approach to produce Taxol, and BT2 can serve as a potential material for fungus engineering to improve Taxol production.
引用
收藏
页码：875 / 877
页数：3
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