Epidemiology and disease burden of tuberculosis in children: a global perspective

被引：108
作者：
Seddon, James A. [1 ]
Shingadia, Delane [2 ]
机构：
[1] Imperial Coll London, Dept Paediat Infect Dis, London, England
[2] Great Ormond St Hosp Sick Children, Dept Paediat Infect Dis, Great Ormond St, London, England
来源：
INFECTION AND DRUG RESISTANCE | 2014年 / 7卷
关键词：
tuberculosis; children; epidemiology; burden; global; MULTIDRUG-RESISTANT TUBERCULOSIS; CHILDHOOD PULMONARY TUBERCULOSIS; MYCOBACTERIUM-TUBERCULOSIS; RISK-FACTORS; PEDIATRIC TUBERCULOSIS; BCG VACCINATION; UNITED-STATES; DRUG-RESISTANT; YOUNG-CHILDREN; CAPE-TOWN;
D O I：
10.2147/IDR.S45090
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Our understanding of the tuberculosis (TB) epidemic in children is incomplete due to challenges in diagnosis and reporting. Children have also been largely excluded from research and advocacy. However, the tide appears to be turning and interest in pediatric TB is increasing. In this article, we explore the epidemiology of childhood TB by first reviewing the natural history of TB in children and the factors that impact on each of the stages from exposure to disease. We then discuss how these factors affect what we see at a country and regional level. Finally, we assess the burden of childhood TB globally.
引用
收藏
页码：153 / 165
页数：13
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