Structure of phosphorus-containing peptide ligands. X-ray and NMR structural study of free ligand and rhodium complex

被引：26

作者：

Gilbertson, SR ^{[1
]}

Chen, GH ^{[1
]}

Kao, J ^{[1
]}

Beatty, A ^{[1
]}

Campana, CF ^{[1
]}

机构：

[1] SIEMENS ANALYT XRAY SYST INC, MADISON, WI 53719 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1997年 / 62卷 / 16期

关键词：

D O I：

10.1021/jo970773e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structure of a series of phosphorus-containing peptides was studied, The X-ray structure of a phosphorus-containing dodecapeptide is reported. Analysis of the solution structure of similar phosphorus-containing peptides before and after coordination of rhodium is also reported. In both the solid state and in solution, the peptides were found to exist in a mixture of a-helical and 3(10) helical conformations. Coordination of rhodium to the i, i + 4 orientated phosphine groups appears to alter the conformational preference.

引用

页码：5557 / 5566

页数：10

共 29 条

[1]

Baum R.M., 1994, C EN 0207, P20

[2] MLEV-17-BASED TWO-DIMENSIONAL HOMONUCLEAR MAGNETIZATION TRANSFER SPECTROSCOPY [J].