A concise synthesis of novel naphtho[a]carbozoles and benzo[c]carbazoles

被引：52

作者：

Pathak, R ^{[1
]}

Nhlapo, JM ^{[1
]}

Govender, S ^{[1
]}

Michael, JP ^{[1
]}

van Otterlo, WAL ^{[1
]}

de Koning, CB ^{[1
]}

机构：

[1] Univ Witwatersrand, Inst Mol Sci, Sch Chem, ZA-2050 Johannesburg, South Africa

来源：

TETRAHEDRON | 2006年 / 62卷 / 12期

基金：

美国安德鲁·梅隆基金会; 新加坡国家研究基金会;

关键词：

Suzuki-Miyaura reaction; carbazoles; antitumour; potassium t-butoxide;

D O I：

10.1016/j.tet.2006.01.012

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from simple indole precursors the synthesis of naphtho[a]carbazoles and benzo[c]carbazoles is described. Key steps include the use of the Suzuki-Miyaura reaction to afford 2- or 3-aryl substituted indoles, as well as a potassium t-butoxide and light assisted aromatic ring-forming reaction. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：2820 / 2830

页数：11

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