Facile synthesis of cycloalkanoindole derivatives by aza-Claisen rearrangement

被引：4

作者：

Kupai, Katalin ^{[1
]}

Banoczi, Gergely ^{[1
]}

Hornyanszky, Gabor ^{[1
]}

Kolonits, Pal ^{[1
]}

Novak, Lajos ^{[1
]}

机构：

[1] Budapest Univ Technol & Econ, Res Grp Alkaloid Chem, Hungarian Acad Sci, Dept Organ Chem & Technol, H-1111 Budapest, Hungary

来源：

MONATSHEFTE FUR CHEMIE | 2012年 / 143卷 / 12期

关键词：

Alzheimer's disease; Physostigmine analogs; Ene reaction; Cyclization; Bromination; ALZHEIMERS-DISEASE; ACETYLCHOLINESTERASE; RIVASTIGMINE; INHIBITORS; DONEPEZIL; SYMPTOMS; DRUG;

D O I：

10.1007/s00706-012-0831-4

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Carba analogs of physostigmine were prepared from aniline derivatives with BF (3) (.) Et2O catalyzed cyclization. Suzuki coupling reactions of the new compounds are also discussed. .

引用

页码：1663 / 1669

页数：7

共 19 条

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