Cinchona derivatives as bifunctional organocatalysts for the direct asymmetric nitroaldol (Henry) reaction

被引：46
|
作者：
Marcelli, T [1 ]
van der Haas, RNS [1 ]
van Maarseveen, JH [1 ]
Hiemstra, H [1 ]
机构：
[1] Univ Amsterdam, Van Hoff Inst Mol Sci, NL-1018 WS Amsterdam, Netherlands
来源：
SYNLETT | 2005年 / 18期
关键词：
asymmetric organocatalysis; bifunctional catalysis; Cinchona alkaloids; nitroaldol reaction; nitroalcohols;
D O I：
10.1055/s-2005-918935
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Bifunctional Cinchona derivatives are asymmetric catalysts for the nitroaldol reaction. Enantiomeric excesses up to 45% have been achieved with activated aromatic aldehydes.
引用
收藏
页码：2817 / 2819
页数：3
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