Polymeric core-shell nanoparticles for therapeutics

被引：58

作者：

Yang, YY ^{[1
]}

Wang, Y ^{[1
]}

Powell, R ^{[1
]}

Chan, P ^{[1
]}

机构：

[1] Inst Bioengn & Nanotechnol, Singapore 138669, Singapore

来源：

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | 2006年 / 33卷 / 5-6期

关键词：

cationic polymer nanoparticles; drug delivery; gene delivery; peptide/protein delivery; polymer core-shell nanoparticles; polymeric nanoparticles;

D O I：

10.1111/j.1440-1681.2006.04408.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. Nanobiotechnologies have recently attracted significant attention from chemists, biologists, engineers and pharmaceutical scientists. In particular, they have been widely applied to improve drug, protein/peptide and gene delivery. 2. This review presents recent advances in the field of drug, protein/peptide and gene delivery using natural and synthetic polymer nanoparticles and explains how polymeric nanoparticles are specifically designed to suit the needs for targeted delivery of small molecular drugs, proteins/peptides and genes. In addition, some of the challenges and prospects for these technologies are discussed.

引用

页码：557 / 562

页数：6

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