Cell biology - Lipid membranes shape up

被引：43
|
作者：
Scales, SJ [1 ]
Scheller, RH [1 ]
机构：
[1] Stanford Univ, Howard Hughes Med Inst, Sch Med, Dept Cellular & Mol Physiol, Stanford, CA 94305 USA
来源：
NATURE | 1999年 / 401卷 / 6749期
关键词：
D O I：
10.1038/43582
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
When synaptic vesicles are recycled, they are 'pinched' off from the presynaptic membrane. A protein called dynamin was thought to be the 'pinchase', but it now turns out that dynamin's function is to recruit another protein, endophilin I, to the neck of the vesicle. Endophilin I affects the composition of the lipids in the vesicle's membrane, influencing its curvature and facilitating the pinching process.
引用
收藏
页码：123 / 124
页数：2
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