A PHASE 2, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, ASCENDING DOSE STUDY TO EVALUATE EFFICACY, SAFETY, AND TOLERABILITY OF CC 220 IN SUBJECTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

被引：0
|
作者：
Furie, R. [1 ]
Werth, V. P. [2 ,3 ]
Lee, E. [4 ]
Box, E. [5 ]
Fondal, M. [6 ]
Kivitz, A. [7 ]
Chatham, W. W. [8 ]
Kalunian, K. C. [9 ]
Legerton, C. [10 ]
Anolik, J. H. [11 ]
Korish, S. [12 ]
Hough, D. R. [12 ]
Weiswasser, M. [12 ]
Choi, S. [12 ]
Schafer, P. [12 ]
机构：
[1] Hofstra Northwell Sch Med, Northwell Hlth, Div Rheumatol, New Hyde Pk, NY USA
[2] Hosp Univ Penn, Dept Dermatol, 3400 Spruce St, Philadelphia, PA 19104 USA
[3] Vet Adm Med Ctr, Philadelphia, PA 19104 USA
[4] Inland Rheumatol Clin Trials Inc, Upland, CA USA
[5] Carolinas PLLC, Box Arthrit & Rheumatol, Charlotte, NC USA
[6] Arthrit Res & Treatment Ctr, Stockbridge, GA USA
[7] Altoona Ctr Clin Res, Duncansville, PA USA
[8] Univ Alabama Birmingham, Rheumatol & Clin Immunol, Birmingham, AL USA
[9] UC San Diego Hlth, Div Rheumatol, San Diego, CA USA
[10] Low Country Rheumatol PA, Charleston, SC USA
[11] Univ Rochester, Med Ctr, Div Allergy Immunol & Rheumatol, Rochester, NY 14642 USA
[12] Celgene Corp, Summit, NJ USA
来源：
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY | 2016年 / 34卷 / 04期
关键词：
CC-220; Ikaros; cereblon;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
P5:94
引用
收藏
页码：S77 / S77
页数：1
相关论文
共 50 条
  • [1] A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, ASCENDING-DOSE, SAFETY STUDY OF CC-220 IN SUBJECTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
    Werth, V. P.
    Furie, R.
    Korish, S.
    Weiswasser, M.
    Azaryan, A.
    Schafer, P. H.
    Delev, N.
    Choi, S.
    Hough, D.
    ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 870 - 871
  • [2] A Randomized, Placebo-Controlled, Double-Blind, Ascending-Dose, Safety, and Pharmacokinetics Study of CC-220 in Subjects with Systemic LUPUS Erythematosus
    Furie, Richard
    Werth, Victoria P.
    Gaudy, Allison
    Ye, Ying
    Korish, Shimon
    Azaryan, Ada
    Delev, Nikolay
    Hough, Douglas
    Weiswasser, Michael
    Choi, Suktae
    Schafer, Peter
    ARTHRITIS & RHEUMATOLOGY, 2017, 69
  • [3] A phase 2, randomized, placebo-controlled, double-blind, ascending dose study to evaluate efficacy, safety, tolerability, pharmacokinetics, pharmacodynamics & pharmacogenetics of CC-220 in subjects with SLE
    Werth, V.
    Furie, R.
    Hough, D.
    Korish, S.
    Weiswasser, M.
    Azarian, A.
    Schafer, P.
    Delev, N.
    Choi, S.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (05) : S65 - S65
  • [4] Bromocriptine in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled study
    Alvarez-Nemegyei, J
    Cobarrubias-Cobos, A
    Escalante-Triay, F
    Sosa-Munoz, J
    Miranda, JM
    Jara, LJ
    LUPUS, 1998, 7 (06) : 414 - 419
  • [5] A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Ascending Single Dose Study to Evaluate the Safety, Tolerability and Pharmacodynamics of AMG145
    Dias, Clapton
    Shaywitz, Adam
    Smith, Brian
    Emery, Maurice
    Bing, Gao
    Gibbs, John
    Wishner, Bill
    Stolman, Dina
    Crispino, Caroline
    Crispino, Caroline
    Cook, Blaire
    Colbert, Alex
    Retter, Marc
    Xu, Ren
    Matson, Mark
    CIRCULATION, 2011, 124 (21)
  • [6] Phase I, Randomized, Double-Blind, Placebo-Controlled, Multiple Intravenous, Dose-Ascending Study of Sirukumab in Cutaneous or Systemic Lupus Erythematosus
    Szepietowski, Jacek C.
    Nilganuwong, Surasak
    Wozniacka, Anna
    Kuhn, Annegret
    Nyberg, Filippa
    van Vollenhoven, Ronald F.
    Bengtsson, Anders A.
    Reich, Adam
    de Vries, Dick E.
    van Hartingsveldt, Bart
    Robinson, Donald W., Jr.
    Gordon, Robert
    Hsu, Benjamin
    ARTHRITIS AND RHEUMATISM, 2013, 65 (10): : 2661 - 2671
  • [7] Iberdomide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled, ascending-dose, phase 2a study
    Furie, Richard A.
    Hough, Douglas R.
    Gaudy, Allison
    Ye, Ying
    Korish, Shimon
    Delev, Nikolay
    Weiswasser, Michael
    Zhan, Xiaojiang
    Schafer, Peter H.
    Werth, Victoria P.
    LUPUS SCIENCE & MEDICINE, 2022, 9 (01):
  • [8] A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Ascending Multiple Oral Doses of CC 930 in Healthy Volunteers
    Kong, Linghui
    Ye, Ying
    Liu, Liangang
    Reyes, Josephine
    Wan, Yuntao
    Wu, Anfan
    Lau, Henry
    Laskin, Oscar
    JOURNAL OF CLINICAL PHARMACOLOGY, 2011, 51 (09): : 1343 - 1343
  • [9] A Double-blind, Placebo-controlled, Randomized, Single Ascending, and Multiple Dose Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral Dose Isomyosamine Capsules in Healthy Adult Subjects
    Brager, Jenna
    Chapman, Chris
    Dunn, Leonard
    Kaplin, Adam
    DRUG RESEARCH, 2023, 73 (02) : 95 - 104
  • [10] Double-blind, randomized, placebo-controlled pilot study of leflunomide in systemic lupus erythematosus
    Tam, LS
    Li, EK
    Wong, CK
    Lam, CWK
    Szeto, CC
    LUPUS, 2004, 13 (08) : 601 - 604
12345