Stereotactic Body Radiation Therapy for Treatment of Primary and Metastatic Pulmonary Malignancies

被引:13
作者
Kelsey, Chris R. [1 ]
Salama, Joseph K. [1 ]
机构
[1] Duke Univ, Med Ctr, Duke Canc Inst, Dept Radiat Oncol, Durham, NC 27710 USA
关键词
Stereotactic body radiation therapy; Stereotactic ablative radiotherapy; Lung cancer; Pulmonary metastases; Surgery; CELL LUNG-CANCER; SINGLE-DOSE RADIOTHERAPY; PHASE I/II TRIAL; CHEST-WALL PAIN; STAGE-I; RADICAL RADIOTHERAPY; CLINICAL-OUTCOMES; LOCAL RECURRENCE; ELDERLY-PATIENTS; FRACTIONS;
D O I
10.1016/j.soc.2013.02.011
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Stereotactic body radiation therapy (SBRT) has become the preferred treatment approach for patients with stage I non-small cell lung cancer who are medically inoperable or refuse surgery. SBRT consists of 3 to 5 radiation treatments delivered over a 10- to 14-day period. Local control is achieved in approximately 90% of patients, and the risk of toxicity is relatively low. Ongoing studies are examining whether SBRT can replace surgery for certain patients, the optimal dose-fractionation scheme, and how best to treat patients having central tumors near the primary tracheobronchial tree.
引用
收藏
页码:463 / +
页数:20
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