Synthesis and Self-Assembly of a Peptide-Amphiphile as a Drug Delivery Vehicle

被引：7

作者：

Son, Soo Jung ^{[1
]}

Brimble, Margaret A. ^{[1
]}

Yang, Sunghyun ^{[1
]}

Harris, Paul W. R. ^{[1
]}

Reddingius, Tom ^{[1
]}

Muir, Benjamin W. ^{[2
]}

Hutt, Oliver E. ^{[2
]}

Waddington, Lynne ^{[2
]}

Guan, Jian ^{[3
]}

Savage, G. Paul ^{[2
]}

机构：

[1] Univ Auckland, Sch Chem Sci, Auckland 1010, New Zealand

[2] CSIRO Mat Sci & Engn, Clayton, Vic 3168, Australia

[3] Univ Auckland, Fac Medicince, Liggins Inst, Auckland 1010, New Zealand

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2013年 / 66卷 / 01期

关键词：

TRIS-LIPIDATION; DESIGN;

D O I：

10.1071/CH12347

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The formation of functional liposomes by the self assembly of a peptide-amphiphile that comprises the neuroprotective tripeptide motif glycyl-prolyl-glutamic acid linked to a hydrophobic moiety is reported. The self-assembled peptide-lipid conjugate displays long range order and can be dispersed as nanometre sized particles.

引用

页码：23 / 29

页数：7

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