A NIR fluorescent probe: imaging endogenous hydrogen peroxide during an autophagy process induced by rapamycin

被引：41

作者：

Xu, Feng ^{[1
]}

Li, Haidong ^{[1
]}

Yao, Qichao ^{[1
]}

Fan, Jiangli ^{[1
]}

Wang, Jingyun ^{[2
]}

Peng, Xiaojun ^{[1
]}

机构：

[1] Dalian Univ Technol, State Key Lab Fine Chem, 2 Linggong Rd, Dalian 116024, Peoples R China

[2] Dalian Univ Technol, Sch Life Sci & Biotechnol, 2 Linggong Rd, Dalian 116024, Peoples R China

来源：

JOURNAL OF MATERIALS CHEMISTRY B | 2016年 / 4卷 / 46期

基金：

美国国家科学基金会;

关键词：

LIVING CELLS; IN-VIVO; OXIDATIVE STRESS; MITOCHONDRIA; ROS; STRATEGIES; DISEASES; H2O2;

D O I：

10.1039/c6tb02463g

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

In this work, a near-infrared probe (Cy-B) with high sensitivity, and good specificity as well as photo-stability has been developed for monitoring both exogenous and endogenous H2O2 in living cells. To the best of our knowledge, it was applied successfully for the first time to monitor spontaneous hydrogen peroxide in an autophagy process induced by the stimulation of rapamycin. The mice imaging experiments indicate that the probe has a good potential to be employed in the imaging of living biological systems.

引用

页码：7363 / 7367

页数：5

共 50 条

[1] A two-photon NIR-to-NIR fluorescent probe for imaging hydrogen peroxide in living cells
Li, Haidong
Yao, Qichao
Fan, Jiangli
Du, Jianjun
Wang, Jingyun
Peng, Xiaojun
BIOSENSORS & BIOELECTRONICS, 2017, 94 : 536 - 543
[2] A lysosome targetable fluorescent probe for endogenous imaging of hydrogen peroxide in living cells
Reja, Shahi Imam
Gupta, Muskan
Gupta, Neha
Bhalla, Vandana
Ohri, Puja
Kaur, Gurcharan
Kumar, Manoj
CHEMICAL COMMUNICATIONS, 2017, 53 (26) : 3701 - 3704
[3] Designing an ESIPT-based fluorescent probe for imaging of hydrogen peroxide during the ferroptosis process
Zhang, Han-Chen
Tian, Di-Hua
Zheng, Ya-Long
Dai, Fang
Zhou, Bo
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2021, 248
[4] Imaging of Endogenous Hydrogen Peroxide during the Process of Cell Mitosis and Mouse Brain Development with a Near-Infrared Ratiometric Fluorescent Probe
Guo, Hailong
Chen, Guang
Gao, Min
Wang, Rui
Liu, Yuxia
Yu, Fabiao
ANALYTICAL CHEMISTRY, 2019, 91 (01) : 1203 - 1210
[5] A new simple fluorescent probe for imaging endogenous hydrogen peroxide in RAW 264.7 cells
Wei, Huiqin
Chen, Huijia
Liu, Shun
Tan, Meixia
Zhang, Zhiqiang
Xu, Xiuzhi
Ke, Fang
TETRAHEDRON LETTERS, 2023, 132
[6] Endogenous CO imaging in bacterial pneumonia with a NIR fluorescent probe
Zhu, Beitong
Xing, Xuejian
Kim, Jungryun
Rha, Hyeonji
Liu, Chun
Zhang, Qiang
Zeng, Lintao
Lan, Minhuan
Kim, Jong Seung
BIOMATERIALS, 2024, 304
[7] A NIR fluorescent probe for the in vitro and in vivo selective detection of hydrogen peroxide
Chunpo, Ge
Yan, Yang
Pengfei, Tan
Hu, Shi
Yibo, Jin
Yuyang, Shang
Yun, Yang
Feng, Ren
SENSORS AND ACTUATORS B-CHEMICAL, 2022, 350
[8] An acetate-based NIR fluorescent probe for selectively imaging of hydrogen peroxide in living cells and in vivo
Xiong, Jiacheng
Xia, Lili
Li, Lushen
Cui, Mengyuan
Gu, Yueqing
Wang, Peng
SENSORS AND ACTUATORS B-CHEMICAL, 2019, 288 : 127 - 132
[9] Ratiometric two-photon fluorescent probe for imaging hydrogen peroxide during stroke-induced ferroptosis
Jian, Zhihong
Ye, Yingze
Yu, Kai
Hu, Wei
Zhu, Hua
Wang, Jin
Xiong, Xiaoxing
Li, Chunya
Gu, Lijuan
SENSORS AND ACTUATORS B-CHEMICAL, 2024, 417
[10] Amyloid-β guided responsive theranostic fluorescent probe for imaging of endogenous hydrogen peroxide in Alzheimer disease
Yang, Yuncong
Wang, Chengke
Xue, Huanxin
Chen, Pinyou
Li, Hung-Wing
Wong, Man Shing
SENSORS AND ACTUATORS B-CHEMICAL, 2024, 406

← 1 2 3 4 5 →