Computerized Working Memory Training for Children with Moderate to Severe Traumatic Brain Injury: A Double-Blind, Randomized, Placebo-Controlled Trial

被引:43
作者
Phillips, Natalie Lynette [1 ,2 ]
Mandalis, Anna [3 ]
Benson, Suzanne [5 ]
Parry, Louise [3 ,4 ]
Epps, Adrienne [4 ]
Morrow, Angie [5 ]
Lah, Suncica [1 ,2 ]
机构
[1] Univ Sydney, Sch Psychol, Brennan MacCallum Bldg A18, Sydney, NSW 2006, Australia
[2] ARC Ctr Excellence Cognit & Its Disorders, Sydney, NSW, Australia
[3] Sydney Childrens Hosp Randwick, Dept Psychol, Sydney, NSW, Australia
[4] Sydney Childrens Hosp Randwick, Brain Injury Rehabil Program, Sydney, NSW, Australia
[5] Childrens Hosp Westmead, Kids Rehab, Sydney, NSW, Australia
关键词
cognitive training; pediatric; randomized controlled trial; traumatic brain injury; working memory; COGNITIVE REHABILITATION; ADHD; ADOLESCENTS; ATTENTION; DEFICITS; OUTCOMES; LIFE;
D O I
10.1089/neu.2015.4358
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Pediatric traumatic brain injury (TBI) places children at risk for deficits in working memory (WM; comprising a central executive [CE], and two storage systems: phonological loop [PL] and visuospatial sketchpad [VSSP]), which is strongly related to attention and academic skills in childhood. This study aimed to examine whether different components of WM can be improved following adaptive WM training (Cogmed) and whether improvements in WM generalize to other cognitive (attention) and academic skills (reading and mathematics) in children with TBI. Twenty-seven children with moderate to severe TBI were randomized to adaptive (Cogmed; n = 13) or non-adaptive training (active placebo; n = 14) and evaluated at baseline, post-training, and 3-months follow-up. Three children in the adaptive group and one child in the non-adaptive group withdrew from the study before completion of training. Complete case (CC) and intention-to-treat (ITT) analyses were conducted. Children in the adaptive group demonstrated significantly greater gains on select WM tasks (VSSP, but not PL or CE) from pre-to post-training (pre-post) and pre-training to follow-up (pre-follow-up; CC and ITT analyses). No gains were found on tests of attention. Adaptive training resulted in significantly greater gains on select academic skills (reading, but not mathematics): reading comprehension pre-post-training (ITT analyses) and reading accuracy pre-follow-up (CC and ITT analyses). This first, to our knowledge, study to examine the efficacy of adaptive WM training for children with TBI provides preliminary evidence of near and far transfer of training to WM and academic skills, respectively.
引用
收藏
页码:2097 / 2104
页数:8
相关论文
共 56 条
[1]   Can computerized working memory training improve impaired working memory, cognition and psychological health? [J].
Akerlund, Elisabeth ;
Esbjornsson, Eva ;
Sunnerhagen, Katharina S. ;
Bjorkdahl, Ann .
BRAIN INJURY, 2013, 27 (13-14) :1649-1657
[2]  
Alloway T. P., 2007, Automated Working Memory Assessment
[3]   Working memory across the lifespan: A cross-sectional approach [J].
Alloway, Tracy Packiam ;
Alloway, Ross G. .
JOURNAL OF COGNITIVE PSYCHOLOGY, 2013, 25 (01) :84-93
[4]   Working memory and cognitive styles in adolescents' attainment [J].
Alloway, Tracy Packiam ;
Banner, Gloria E. ;
Smith, Patrick .
BRITISH JOURNAL OF EDUCATIONAL PSYCHOLOGY, 2010, 80 (04) :567-581
[5]  
[Anonymous], 1974, PSYCHOL LEARN MOTIV, DOI DOI 10.1016/S0079-7421(08)60452-1
[6]  
[Anonymous], 2016, Test of everyday attention for children. (TEACh2)
[7]   Cognitive Training Enhances Intrinsic Brain Connectivity in Childhood [J].
Astle, Duncan E. ;
Barnes, Jessica J. ;
Baker, Kate ;
Colclough, Giles L. ;
Woolrich, Mark W. .
JOURNAL OF NEUROSCIENCE, 2015, 35 (16) :6277-6283
[8]   Neurocognitive Outcomes and Recovery After Pediatric TBI: Meta-Analytic Review of the Literature [J].
Babikian, Talin ;
Asarnow, Robert .
NEUROPSYCHOLOGY, 2009, 23 (03) :283-296
[9]   The episodic buffer: a new component of working memory? [J].
Baddeley, A .
TRENDS IN COGNITIVE SCIENCES, 2000, 4 (11) :417-423
[10]   Effect of working memory training on working memory, arithmetic and following instructions [J].
Bergman-Nutley, Sissela ;
Klingberg, Torkel .
PSYCHOLOGICAL RESEARCH-PSYCHOLOGISCHE FORSCHUNG, 2014, 78 (06) :869-877