C-Type Lectins in Veterinary Species: Recent Advancements and Applications

被引：18

作者：

Lindenwald, Dimitri Leonid

Lepenies, Bernd ^{[1
]}

机构：

[1] Univ Vet Med Hannover, Immunol Unit, D-30559 Hannover, Germany

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2020年 / 21卷 / 14期

关键词：

C-type lectin; glycans; immune modulation; comparative immunology; veterinary immunology; BETA-GLUCAN RECOGNITION; DENDRITIC CELLS; PATHOGEN RECOGNITION; DC-SIGN; RECEPTOR; EXPRESSION; INNATE; DECTIN-1; MINCLE; IDENTIFICATION;

D O I：

10.3390/ijms21145122

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

C-type lectins (CTLs), a superfamily of glycan-binding receptors, play a pivotal role in the host defense against pathogens and the maintenance of immune homeostasis of higher animals and humans. CTLs in innate immunity serve as pattern recognition receptors and often bind to glycan structures in damage- and pathogen-associated molecular patterns. While CTLs are found throughout the whole animal kingdom, their ligand specificities and downstream signaling have mainly been studied in humans and in model organisms such as mice. In this review, recent advancements in CTL research in veterinary species as well as potential applications of CTL targeting in veterinary medicine are outlined.

引用

收藏

页码：1 / 16

页数：16

相关论文

共 144 条

[1] Bacterial glycans and their interactions with lectins in the innate immune system [J].

Acosta, Mariano Prado ;

Lepenies, Bernd .

BIOCHEMICAL SOCIETY TRANSACTIONS, 2019, 47 :1569-1579

[2] Single nucleotide variants in innate immune genes associated with Salmonella shedding and colonization in swine on commercial farms [J].

Ainslie-Garcia, Margaret H. ;

Farzan, Abdolvahab ;

Jafarikia, Mohsen ;

Lillie, Brandon N. .

VETERINARY MICROBIOLOGY, 2018, 219 :171-177

[3] Molecular Detection of Leishmania spp. in Skin and Blood of Stray Dogs from Endemic Areas of Cutaneous Leishmaniasis in Saudi Arabia [J].

Alanazi, Abdullah D. ;

Puschendorf, Robert ;

Alyousif, Mohamed S. ;

Al-Khalifa, Mohamed S. ;

Alharbi, Samir A. ;

AL-Shehri, Zafer S. ;

Said, Ashraf E. ;

Alanazi, Ibrahim O. ;

AL-Mohammed, Hamdan, I ;

Alraey, Yasser A. .

IRANIAN JOURNAL OF PARASITOLOGY, 2019, 14 (02) :231-239

[4] Characterization of the Porcine CLEC12A and Analysis of Its Expression on Blood Dendritic Cell Subsets [J].

Alvarez, Belen ;

Nieto-Pelegrin, Elvira ;

Martinez de la Riva, Paloma ;

Toki, Daisuke ;

Poderoso, Teresa ;

Revilla, Concepcion ;

Uenishi, Hirohide ;

Ezquerra, Angel ;

Dominguez, Javier .

FRONTIERS IN IMMUNOLOGY, 2020, 11

[5] Comparison of innate and Th1-type host immune responses in Oesophagostomum dentatum and Trichuris suis infections in pigs [J].

Andreasen, A. ;

Skovgaard, K. ;

Klaver, E. J. ;

Van Die, I. ;

Mejer, H. ;

Thamsborg, S. M. ;

Kringel, H. .

PARASITE IMMUNOLOGY, 2016, 38 (01) :53-63

[6]

Anwar H, 2019, INT J MED MUSHROOMS, V21, P79, DOI [10.1615/IntJMedMushrooms.2018029348, 10.1615/intjmedmushrooms.2018029348]

[7] Cell type-specific differences in β-glucan recognition and signalling in porcine innate immune cells [J].

Baert, Kim ;

Sonck, Eva ;

Goddeeris, Bruno M. ;

Devriendt, Bert ;

Cox, Eric .

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 48 (01) :192-203

[8] Genome-wide association analysis in dogs implicates 99 loci as risk variants for anterior cruciate ligament rupture [J].

Baker, Lauren A. ;

Kirkpatrick, Brian ;

Rosa, Guilherme J. M. ;

Gianola, Daniel ;

Valente, Bruno ;

Sumner, Julia P. ;

Baltzer, Wendy ;

Hao, Zhengling ;

Binversie, Emily E. ;

Volstad, Nicola ;

Piazza, Alexander ;

Sample, Susannah J. ;

Muir, Peter .

PLOS ONE, 2017, 12 (04)

[9] Nutraceuticals An Alternative Strategy for the Use of Antimicrobials [J].

Ballou, Michael A. ;

Davis, Emily M. ;

Kasl, Benjamin A. .

VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE, 2019, 35 (03) :507-+

[10] Lentinan produces a robust antidepressant-like effect via enhancing the prefrontal Dectin-1/AMPA receptor signaling pathway [J].

Bao, Hongkun ;

Sun, Lijuan ;

Zhu, Ying ;

Ran, Pengzhan ;

Hu, Weihong ;

Zhu, Keming ;

Li, Bai ;

Hou, Yangyang ;

Nie, Jun ;

Gao, Tangxin ;

Shan, Liping ;

Du, Kai ;

Zheng, Shangyong ;

Zheng, Bingrong ;

Xiao, Chunjie ;

Du, Jing .

BEHAVIOURAL BRAIN RESEARCH, 2017, 317 :263-271

← 1 2 3 4 5 6 7 8 9 10 →