The Problem With Asymptomatic Cerebral Embolic Complications in Vascular Procedures What If They Are Not Asymptomatic?

被引:30
作者
Gress, Daryl R. [1 ]
机构
[1] Univ Virginia, Dept Neurol, Charlottesville, VA 22908 USA
关键词
asymptomatic stroke; cognitive decline; dementia; diffusion-weighted imaging; silent stroke; INFARCTS;
D O I
10.1016/j.jacc.2012.06.037
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cerebral embolic events related to carotid and cardiac disease have been known for decades. Recently, cerebral embolic events have become a focus of clinical importance as complications of vascular procedures. Further, the development of new technologies and procedures has increased the overall clinical significance. Although the relative safety of these procedures is usually defined by acute stroke risk, it is also becoming clear that far more subclinical events are occurring. Recent reports provided substantial evidence of memory loss, cognitive decline, and dementia related to these so-called silent infarcts. Literature reports of magnetic resonance imaging events lead to an estimate of as many as 600,000 patients with new brain injury each year in the United States alone. Given the magnitude of the numbers involved, the impact of accelerated cognitive loss and premature senescence in a vulnerable at-risk population could well be significant. (J Am Coll Cardiol 2012;60:1614-6) (C) 2012 by the American College of Cardiology Foundation
引用
收藏
页码:1614 / 1616
页数:3
相关论文
共 6 条
  • [1] Microinfarct Pathology, Dementia, and Cognitive Systems
    Arvanitakis, Zoe
    Leurgans, Sue E.
    Barnes, Lisa L.
    Bennett, David A.
    Schneider, Julie A.
    [J]. STROKE, 2011, 42 (03) : 722 - 727
  • [2] Silent cerebral ischaemia: hidden fingerprints of invasive medical procedures
    Bendszus, M
    Stoll, G
    [J]. LANCET NEUROLOGY, 2006, 5 (04) : 364 - 372
  • [3] Memory after silent stroke Hippocampus and infarcts both matter
    Blum, S.
    Luchsinger, J. A.
    Manly, J. J.
    Schupf, N.
    Stern, Y.
    Brown, T. R.
    DeCarli, C.
    Small, S. A.
    Mayeux, R.
    Brickman, A. M.
    [J]. NEUROLOGY, 2012, 78 (01) : 38 - 46
  • [4] Bonati LH, 2010, LANCET NEUROL, V9, P353, DOI 10.1016/S1474-4422(10)70057-0
  • [5] New brain lesions after carotid stenting versus carotid endarterectomy -: A systematic review of the literature
    Schnaudigel, Sonja
    Groeschel, Klaus
    Pilgram, Sara M.
    Kastrup, Andreas
    [J]. STROKE, 2008, 39 (06) : 1911 - 1919
  • [6] Effect of infarcts on dementia in the Baltimore Longitudinal Study of Aging
    Troncoso, Juan C.
    Zonderman, Alan B.
    Resnick, Susan M.
    Crain, Barbara
    Pletnikova, Olga
    O'Brien, Richard J.
    [J]. ANNALS OF NEUROLOGY, 2008, 64 (02) : 168 - 176