Pulmonary Langerhans Cell Histiocytosis: A not so Benign Lesion

被引:1
作者
Halder, Rohan [1 ]
Anantharaman, Meenakshi B. [1 ]
Seth, Tulika [1 ]
Mahapatra, Manoranjan [1 ]
Saxena, Renu [1 ]
机构
[1] AIIMS, Dept Hematol, New Delhi 110029, India
关键词
pulmonary LCH; multisystem disease; etoposide in LCH; CHILDREN; DISEASE;
D O I
10.1097/MPH.0000000000001371
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Langerhans cell histiocytosis is a multisystem disease affecting young children. Lung involvement has a myriad of manifestations and the outcomes for these patients have been poorly defined. We present a 2-year-old child who presented with multisystem disease with multiple lung cysts. Treatment consisted of multiagent chemotherapy for 18 months and was associated with a slow but favorable response.
引用
收藏
页码:E122 / E124
页数:3
相关论文
共 9 条
  • [1] Outcome in children with pulmonary Langerhans cell Histiocytosis
    Braier, J
    Latella, A
    Balancini, B
    Castaños, C
    Rosso, D
    Chantada, G
    Ripoli, M
    Goldberg, J
    [J]. PEDIATRIC BLOOD & CANCER, 2004, 43 (07) : 765 - 769
  • [2] Donadieu J, 1996, ARCH DIS CHILD, V75, P17
  • [3] Egeler RM, 1999, BLOOD, V94, P4195
  • [4] HA SY, 1992, PEDIATRICS, V89, P466
  • [5] Langerhans cell histiocytosis (LCH): Guidelines for diagnosis, clinical work-up, and treatment for patients till the age of 18 years
    Haupt, Riccardo
    Minkov, Milen
    Astigarraga, Itziar
    Schaefer, Eva
    Nanduri, Vasanta
    Jubran, Rima
    Egeler, R. Maarten
    Janka, Gritta
    Micic, Dragan
    Rodriguez-Galindo, Carlos
    Van Gool, Stefaan
    Visser, Johannes
    Weitzman, Sheila
    Donadieu, Jean
    [J]. PEDIATRIC BLOOD & CANCER, 2013, 60 (02) : 175 - 184
  • [6] Pulmonary Langerhans cell histiocytosis: A variable disease in childhood
    Odame, Isaac
    Li, Patricia
    Lau, Loretta
    Doda, Wendy
    Noseworthy, Mary
    Babyn, Paul
    Weitzman, Sheila
    [J]. PEDIATRIC BLOOD & CANCER, 2006, 47 (07) : 889 - 893
  • [7] Pulmonary and mediastinal lesions in children with Langerhans cell histiocytosis
    Smets, A
    Mortele, K
    DePraeter, G
    Francois, O
    Benoit, Y
    Kunnen, M
    [J]. PEDIATRIC RADIOLOGY, 1997, 27 (11) : 873 - 876
  • [8] The 5-Year EFS of Multisystem LCH With Risk-Organ Involvement Is Suboptimal: A Single-center Experience From India
    Totadri, Sidharth
    Bansal, Deepak
    Trehan, Amita
    Srinivasan, Radhika
    Varma, Neelam
    Kakkar, Nandita
    Saxena, Akshay K.
    Bhatia, Prateek
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2016, 38 (01) : E1 - E5
  • [9] PULMONARY LANGERHANS CELL GRANULOMATOSIS (HISTIOCYTOSIS-X) - A CLINICOPATHOLOGICAL STUDY OF 48 CASES
    TRAVIS, WD
    BOROK, Z
    ROUM, JH
    ZHANG, J
    FEUERSTEIN, I
    FERRANS, VJ
    CRYSTAL, RG
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1993, 17 (10) : 971 - 986