A rationally designed universal catalyst for Suzuki-Miyaura coupling processes

被引：827

作者：

Walker, SD ^{[1
]}

Barder, TE ^{[1
]}

Martinelli, JR ^{[1
]}

Buchwald, SL ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 14期

关键词：

aryl chlorides; boronic acids; cross-coupling; palladium; phosphane ligands;

D O I：

10.1002/anie.200353615

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Unprecedented scope, reactivity, and stability are displayed by a new catalyst system. This was demonstrated with general and efficient syntheses of sterically hindered (hetero)biaryls (see examples shown), mild coupling reactions of alkyl boron derivatives, and rapid coupling reactions of aryl chlorides at room temperature.

引用

收藏

页码：1871 / 1876

页数：6

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