Gold-catalyzed oxycyclization of allenic carbamates: expeditious synthesis of 1,3-oxazin-2-ones

被引：31

作者：

Alcaide, Benito ^{[1
]}

Almendros, Pedro ^{[2
]}

Teresa Quiros, M. ^{[1
]}

Fernandez, Israel ^{[3
]}

机构：

[1] Univ Complutense Madrid, Fac Quim, CSIC,Dept Quim Organ 1, Unidad Asociada,Grp Lactamas & Heterociclos Bioac, E-28040 Madrid, Spain

[2] CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain

[3] Univ Complutense Madrid, Fac Quim, Dept Quim Organ 1, E-28040 Madrid, Spain

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 9卷

关键词：

allenes; computational chemistry; gold; gold catalysis; heterocycles; reaction mechanisms; THERMODYNAMICALLY FAVORED ISOMERS; TERT-BUTYL CARBONATES; HYBRID MOLECULES; CYCLIZATION; ISOMERIZATION; PRODUCT; ALKYNES; ACCESS; SEMISYNTHESIS; DERIVATIVES;

D O I：

10.3762/bjoc.9.93

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A combined experimental and computational study on regioselective gold-catalyzed synthetic routes to 1,3-oxazinan-2-ones (kinetically controlled products) and 1,3-oxazin-2-one derivatives (thermodynamically favored) from easily accessible allenic carbamates has been carried out.

引用

页码：818 / 826

页数：9

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