Cerebral Organoids in a Dish: Progress and Prospects

被引：42

作者：

Bershteyn, Marina ^{[1
,2
]}

Kriegstein, Arnold R. ^{[1
,2
,3
]}

机构：

[1] Eli & Edythe Broad Ctr Regenerat Med & Stem Cell, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA

来源：

CELL | 2013年 / 155卷 / 01期

关键词：

PLURIPOTENT STEM-CELLS;

D O I：

10.1016/j.cell.2013.09.010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.

引用

页码：19 / 20

页数：2

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