Detection of canine herpesvirus DNA in the ganglionic neurons and the lymph node lymphocytes of latently infected dogs

被引：62

作者：

Miyoshi, M ^{[1
]}

Ishii, Y

Takiguchi, M

Takada, A

Yasuda, J

Hashimoto, A

Okazaki, K

Kida, H

机构：

[1] Hokkaido Univ, Grad Sch Vet Med, Dept Vet Clin Sci, Sapporo, Hokkaido 0600818, Japan

[2] Hokkaido Univ, Vet Teaching Hosp, Fac Med Vet, Sapporo, Hokkaido 0600818, Japan

[3] Hokkaido Univ, Grad Sch Vet Med, Dept Dis Control, Sapporo, Hokkaido 0600818, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 1999年 / 61卷 / 04期

关键词：

canine herpesvirus; ganglionic neuron; latency; lymphocyte;

D O I：

10.1292/jvms.61.375

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

TO determine the site of latent infection of canine herpesvirus (CHV), tissues from dogs convalescent from acute infection with CHV were examined for the presence of viral genome DNA by the nested polymerase chain reaction. CHV DNA was detected in the trigeminal ganglia and the retropharyngeal lymph nodes. In situ hybridization study of the tissues revealed that CHV genome persisted in the nuclei of ganglionic neurons and lymphocytes.

引用

页码：375 / 379

页数：5

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