The underrepresentation of older adults in clinical trials of Janus kinase inhibitors in the treatment of atopic dermatitis

被引：7

作者：

Sreekantaswamy, Shreya A. ^{[1
]}

Tully, Janell ^{[2
,3
]}

Edelman, Linda S. ^{[4
]}

Supiano, Mark A. ^{[5
]}

Butler, Daniel

机构：

[1] Univ Utah, Sch Med, Salt Lake City, UT USA

[2] Univ Calif San Francisco, Dept Dermatol, San Francisco, CA USA

[3] Univ Arizona, Coll Med, Phoenix, AZ USA

[4] Univ Utah, Coll Nursing, Salt Lake City, UT USA

[5] Univ Utah, Div Geriatr, Salt Lake City, UT USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2022年 / 87卷 / 05期

关键词：

atopic dermatitis; clinical trials; eczema; geriatric; JAK inhibitors; older adults;

D O I：

10.1016/j.jaad.2022.02.051

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

[No abstract available]

引用

页码：1174 / 1176

页数：3

共 5 条

[1] Never too old?: Age should not be a barrier to enrollment in cancer clinical trials [J].

Aapro, MS ;

Köhne, CH ;

Cohen, HJ ;

Extermann, M .

ONCOLOGIST, 2005, 10 (03) :198-204

[2] The epidemiology of atopic dermatitis in older adults: A population-based study in the United Kingdom [J].

Chan, Leslie N. ;

Magyari, Alexa ;

Ye, Morgan ;

Al-Alusi, Noor A. ;

Langan, Sinead M. ;

Margolis, David ;

McCulloch, Charles E. ;

Abuabara, Katrina .

PLOS ONE, 2021, 16 (10)

[3] Inclusion of Older Adults in Randomized Clinical Trials for Systemic Medications for Atopic Dermatitis: A Systematic Review [J].

Lam, Megan ;

Zhu, Jie Wei ;

Maqbool, Talha ;

Adam, Gaelen ;

Tadrous, Mina ;

Rochon, Paula ;

Drucker, Aaron M. .

JAMA DERMATOLOGY, 2020, 156 (11) :1240-1245

[4]

Pfizer, PFIZ SHAR COPR ENDP

[5] Under-representation of elderly in clinical trials: An analysis of the initial approval documents in the Food and Drug Administration database [J].

Ruiter, Rikje ;

Burggraaf, Jacobus ;

Rissmann, Robert .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2019, 85 (04) :838-844

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