Development of Treatment Concepts for the Use of Botulinum Toxin A in Children with Cerebral Palsy

被引：8

作者：

Placzek, Richard ^{[1
]}

Siebold, Dagmar ^{[2
]}

Funk, Julia F. ^{[1
]}

机构：

[1] Charite, Ctr Musculoskeletal Surg, Dept Paediat Orthopaed, D-13353 Berlin, Germany

[2] Ctr Physiotherapy & Neurorehabil, Berlin, Germany

来源：

TOXINS | 2010年 / 2卷 / 09期

关键词：

botulinum toxin A; cerebral palsy; CP; multi-level treatment; key-muscle concept; GROSS MOTOR FUNCTION; LOWER-LIMB; SPASTICITY; POPULATION; MANAGEMENT; PREVENTION; RECOVERY; SURGERY; SYSTEM; HIP;

D O I：

10.3390/toxins2092258

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

The treatment of children with cerebral palsy with Botulinum toxin A injections is well established, safe and effective. However, a standardized injection strategy is still missing and the used dosage has escalated over the years. In the recent past, the recommended dosages in Europe were, however, reduced due to a better understanding of the relationship between dosage, severe side effects and the kind of anesthesia used. To combine safety and efficacy, the trend tends to a lower dosage, but combined with a more specific selection of injected muscles. The treatment of these key-muscles takes into account the best support for motor development to attain each individual motor milestone.

引用

页码：2258 / 2271

页数：14

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