Empirical likelihood confidence intervals for regression parameters of the survival rate

被引:8
作者
Zhao, Yichuan [1 ]
Yang, Song [2 ]
机构
[1] Georgia State Univ, Dept Math & Stat, Atlanta, GA 30303 USA
[2] NHLBI, Off Biostat Res, Bethesda, MD 20892 USA
关键词
chi-squared distribution; confidence interval; link function; right censoring; QUALITY-ADJUSTED LIFETIME; SEMIPARAMETRIC ANALYSIS; INFERENCE; TERM; CONSISTENCY; MODELS;
D O I
10.1080/10485252.2011.621024
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
The survival probability of patients plays an important role in biomedical settings. Based on the Jung [(1996), 'Regression Analysis for Long-Term Survival Rate', Biometrika, 83, 227-232] regression model for survival probability, Zhao [(2005), 'Regression Analysis for Long-Term Survival Rate Via Empirical Likelihood', Journal of Nonparametric Statistics, 17, 995-1007] developed an empirical likelihood (EL) confidence region for the vector of regression parameters. However, the proposed EL method does not work for a subset of regression parameters. In this paper, we develop EL confidence regions for any subset or a linear combination of the vectors of the regression parameters under the regression model. We propose two kinds of confidence intervals for the survival rate of a patient with the given covariates. A simulation study is carried out to compare the proposed method with the normal approximation-based method and nonparametric bootstrap method. Finally, we compare the proposed procedure with the existing method using a clinical trial data set.
引用
收藏
页码:59 / 70
页数:12
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