Folding a focalized acoustical vortex on a flat holographic transducer: Miniaturized selective acoustical tweezers

被引:183
作者
Baudoin, Michael [1 ]
Gerbedoen, Jean-Claude [1 ]
Riaud, Antoine [2 ,4 ]
Matar, Olivier Bou [1 ]
Smagin, Nikolay [1 ]
Thomas, Jean-Louis [3 ]
机构
[1] Univ Lille, Univ Polytech Hauts de France, CNRS,Int Lab LIA LICS, UMR 8520,Cent Lille,ISEN,SATT Nord,IEMN, F-59000 Lille, France
[2] Univ Paris Sorbonne Cite, INSERM UMR S1147, 45 Rue St Peres, F-75270 Paris, France
[3] UPMC Univ Paris 06, Sorbonne Univ, CNRS, UMR 7588,Inst NanoSci Paris, 4 Pl Jussieu, F-75005 Paris, France
[4] Fudan Univ, ASIC & Syst State Key Lab, Sch Microelect, Shanghai 200433, Peoples R China
关键词
RADIATION FORCE; BESSEL BEAM; CELL; VIABILITY;
D O I
10.1126/sciadv.aav1967
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Acoustical tweezers based on focalized acoustical vortices hold the promise of precise contactless manipulation of millimeter down to submicrometer particles, microorganisms, and cells with unprecedented combined selectivity and trapping force. Yet, the widespread dissemination of this technology has been hindered by severe limitations of current systems in terms of performance and/or miniaturization and integrability. Here, we unleash the potential of focalized acoustical vortices by developing the first flat, compact, paired single electrode focalized acoustical tweezers. These tweezers rely on spiraling transducers obtained by folding a spherical acoustical vortex on a flat piezoelectric substrate. We demonstrate the ability of these tweezers to grab and displace micrometric objects in a standard microfluidic environment with unique selectivity. The simplicity of this system and its scalability to higher frequencies open tremendous perspectives in microbiology, microrobotics, and microscopy.
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页数:6
相关论文
共 39 条
[1]   Iso-acoustic focusing of cells for size-insensitive acousto-mechanical phenotyping [J].
Augustsson, Per ;
Karlsen, Jonas T. ;
Su, Hao-Wei ;
Bruus, Henrik ;
Voldman, Joel .
NATURE COMMUNICATIONS, 2016, 7
[2]   Observation of a Single-Beam Gradient Force Acoustical Trap for Elastic Particles: Acoustical Tweezers [J].
Baresch, Diego ;
Thomas, Jean-Louis ;
Marchiano, Regis .
PHYSICAL REVIEW LETTERS, 2016, 116 (02)
[3]   Spherical vortex beams of high radial degree for enhanced single-beam tweezers [J].
Baresch, Diego ;
Thomas, Jean-Louis ;
Marchiano, Regis .
JOURNAL OF APPLIED PHYSICS, 2013, 113 (18)
[4]   Three-dimensional acoustic radiation force on an arbitrarily located elastic sphere [J].
Baresch, Diego ;
Thomas, Jean-Louis ;
Marchiano, Regis .
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 2013, 133 (01) :25-36
[5]   Acoustic radiation- and streaming-induced microparticle velocities determined by microparticle image velocimetry in an ultrasound symmetry plane [J].
Barnkob, Rune ;
Augustsson, Per ;
Laurell, Thomas ;
Bruus, Henrik .
PHYSICAL REVIEW E, 2012, 86 (05)
[6]   THE CONCEPT OF AN ANGULAR SPECTRUM OF PLANE WAVES, AND ITS RELATION TO THAT OF POLAR DIAGRAM AND APERTURE DISTRIBUTION [J].
BOOKER, HG ;
CLEMMOW, PC .
PROCEEDINGS OF THE INSTITUTION OF ELECTRICAL ENGINEERS-LONDON, 1950, 97 (45) :11-17
[7]  
Boyle R., 1925, T ROY SOC CAN, V19, P159
[8]   Microchannel Acoustophoresis does not Impact Survival or Function of Microglia, Leukocytes or Tumor Cells [J].
Burguillos, Miguel A. ;
Magnusson, Cecilia ;
Nordin, Maria ;
Lenshof, Andreas ;
Augustsson, Per ;
Hansson, Magnus J. ;
Elmer, Eskil ;
Lilja, Hans ;
Brundin, Patrik ;
Laurell, Thomas ;
Deierborg, Tomas .
PLOS ONE, 2013, 8 (05)
[9]   Acoustic tweezers via sub-time-of-flight regime surface acoustic waves [J].
Collins, David J. ;
Devendran, Citsabehsan ;
Ma, Zhichao ;
Ng, Jia Wei ;
Neild, Adrian ;
Ai, Ye .
SCIENCE ADVANCES, 2016, 2 (07)
[10]   Two-dimensional single-cell patterning with one cell per well driven by surface acoustic waves [J].
Collins, David J. ;
Morahan, Belinda ;
Garcia-Bustos, Jose ;
Doerig, Christian ;
Plebanski, Magdalena ;
Neild, Adrian .
NATURE COMMUNICATIONS, 2015, 6