Yolk Sac Tumor Arising in Uterine Carcinosarcoma With Endometrioid and Serous Components: A Case Report With Immunohistochemical Analysis

被引：2

作者：

Grindstaff, Samuel ^{[1
]}

Hanley, Linda C. ^{[2
,3
]}

Banet, Natalie ^{[2
,3
]}

机构：

[1] Uniformed Serv Univ Hlth Sci, Dept Pathol, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA

[2] Brown Univ, Women & Infants Hosp, Dept Pathol & Lab Med, 101 Dudley St, Providence, RI 02905 USA

[3] Brown Univ, Warren Alpert Med Sch, 101 Dudley St, Providence, RI 02905 USA

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY | 2022年 / 41卷 / 01期

关键词：

Yolk sac tumor; Carcinosarcoma; HER-2; Uterine serous carcinoma; AMPLIFICATION; EXPERIENCE;

D O I：

10.1097/PGP.0000000000000774

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Yolk sac tumor of the endometrium is an uncommon neoplasm. Here we report a case of yolk sac tumor arising in a uterine carcinosarcoma, with the carcinomatous component showing both endometrioid and serous components, and the sarcomatous component showing homologous (spindled) differentiation. The yolk sac tumor showed predominant glandular configuration and was present admixed with the epithelial components. Extensive immunostaining was performed to narrow the differential diagnosis, including potentially therapeutic testing for HER-2. To our knowledge, this is the first case of carcinosarcoma with this mix of epithelial components and corresponding reporting of these immune and therapeutic markers.

引用

页码：40 / 44

页数：5

共 50 条

[21] Extragonadal yolk sac tumor outside of the midline of the body: a case report of a child with a yolk sac tumor of the pontocerebellar angle
Lazzareschi, Ilaria
Furfaro, Ilaria Francesca
Coccia, Paola
Puma, Nadia
Riccardi, Riccardo
[J]. TUMORI JOURNAL, 2009, 95 (06): : 840 - 842
[22] Yolk sac tumor of the ovary during pregnancy: A case report
Aoki, Y
Higashino, M
Ishii, S
Tanaka, K
[J]. GYNECOLOGIC ONCOLOGY, 2005, 99 (02) : 497 - 499
[23] Yolk sac tumor of endometrium: A case report and literature review
Lin, Shih-Wen
Hsieh, Shu-Wei
Huang, Shih-Hung
Liang, Hung-Shuo
Huang, Chia-Yen
[J]. TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, 2019, 58 (06): : 846 - 848
[24] An unusual clinical presentation of a pure yolk sac tumor of the ovary: case report
Caserta, D.
Ralli, E.
Bordi, G.
Moscarini, M.
[J]. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2013, 34 (06) : 577 - 579
[25] Primary yolk sac tumor of the cerebellar vermis: A case report
Shenoy, Asha S.
Desai, Heena M.
Tyagi, Devendra K.
Savant, Hemant V.
Kavishwar, Vikas S.
Balasubramaniam, Meenakshi
[J]. INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2014, 57 (02) : 278 - 280
[26] Primary yolk sac tumor of orbit: Report of a rare case
Poflee, Sandhya, V
Pawar, Prajkta S.
Gaddewar, Nilesh S.
Raut, Waman K.
[J]. INDIAN JOURNAL OF CANCER, 2020, 57 (03) : 337 - 339
[27] A case of ovarian endometrioid adenocarcinoma with yolk sac tumor in a 35-year-old woman
Hong, D. G.
Chong, G. O.
Seong, W. J.
Lee, Y. S.
Cho, Y. L.
Park, J. Y.
Chae, J. M.
Park, I. S.
[J]. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2010, 31 (04) : 471 - 474
[28] Ovarian yolk sac tumor (YST) in a postmenopausal patient: case report and review of the literature
Stasinopoulou, S.
Vakas, P.
Gioti, E.
Politi, A.
Tsagkas, A.
Papadimitriou, C.
Bournakis, E.
Carvounis, E.
[J]. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2019, 40 (04) : 656 - 662
[29] Relapsed and refractory yolk sac tumor of the peritoneum (mesentery): A case report and literature review
Zhou, Xue
Zhao, Lanbo
Feng, Xue
Pan, Zhenni
Bin, Yadi
Zhang, Siyi
Li, Min
Guo, Miao
Hou, Huilian
Li, Qiling
[J]. FRONTIERS IN ONCOLOGY, 2022, 12
[30] Primary Yolk Sac Tumor in the Cerebellar Vermis. Case Report
Nakamura, Taigen
Kanamori, Masayuki
Sonoda, Yukihiko
Watanabe, Mika
Kumabe, Toshihiro
Tominaga, Teiji
[J]. NEUROLOGICAL SURGERY, 2009, 37 (02): : 173 - 177

← 1 2 3 4 5 →