Thermal behavior of human eye in relation with change in blood perfusion, porosity, evaporation and ambient temperature

Extreme environmental and physiological conditions present challenges for thermal processes in body tissues including multi-layered human eye. A mathematical model has been formulated in this direction to study the thermal behavior of the human eye in relation with the change in blood perfusion, porosity, evaporation and environmental temperatures. In this study, a comprehensive thermal analysis has been performed on the multi-layered eye using Pennes' bio-heat equation with appropriate boundary and interface conditions. The variational finite element method and MATLAB software were used for the solution purpose and simulation of the results. The thermoregulatory effect due to blood perfusion rate, porosity, ambient temperature and evaporation at various regions of human eye was illustrated mathematically and graphically. The main applications of this model are associated with the medical sciences while performing laser therapy and other thermoregulatory investigation on human eye. (C) 2016 Elsevier Ltd. All rights reserved.