Green synthesis of new pyrimido[4,5-d]pyrimidine derivatives using 7-aminonaphthalene-1,3-disulfonic acid-functionalized magnetic Fe3O4@SiO2 nanoparticles as catalyst

被引：23

作者：

Ghorbani-Vaghei, Ramin ^{[1
]}

Sarmast, Narges ^{[1
]}

机构：

[1] Bu Ali Sina Univ, Dept Chem, POB 65174, Hamadan, Iran

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 2018年 / 32卷 / 02期

关键词：

green chemistry; magnetic nanoparticles; N; N-dimethyl 6-amino uracil; phenylisothiocyanate; pyrimido[4; 5-d]pyrimidine; ONE-POT SYNTHESIS; MULTICOMPONENT SYNTHESIS; EFFICIENT SYNTHESIS; SEPARABLE CATALYST; HIGHLY EFFICIENT; SCIENCE;

D O I：

10.1002/aoc.4003

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

We, herein, describe a novel, simple, efficient and one-pot multi-component procedure for the synthesis of substituted pyrimido[4,5-d]pyrimidines via reaction of N,N-dimethyl-6-amino uracil, isothiocyanate and aromatic aldehydes promoted by 7-aminonaphthalene-1,3-disulfonic acid (ANDSA)-functionalized magnetic Fe3O4@SiO2 in water as solvent and without using any other harmful organic reagents. Compared with other reactions, using these organic-inorganic hybrid heterogeneous catalysts can help us to achieve a green procedure, high catalytic activity, easy recovery with an external magnetic field, and short reaction times.

引用

页数：9

共 23 条

[1] The role of catalysis in the design, development, and implementation of green chemistry [J].

Anastas, PT ;

Bartlett, LB ;

Kirchhoff, MM ;

Williamson, TC .

CATALYSIS TODAY, 2000, 55 (1-2) :11-22

[2] An efficient one-pot three-component synthesis of pyrimido[4,5-d]pyrimidine derivatives in aqueous medium [J].

Badvel, Sreedhar ;

Gopireddy, Raveendra Reddy ;

Shaik, Thaslim Basha ;

Hasti, Sudhamani ;

Tummaluru, Veera Reddy ;

Chamarthi, Naga Raju .

CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2015, 51 (08) :749-753

[3] ON THE ORIGIN OF PRODUCT SELECTIVITY IN AQUEOUS DIELS-ALDER REACTIONS [J].

BRESLOW, R ;

MAITRA, U .

TETRAHEDRON LETTERS, 1984, 25 (12) :1239-1240

[4] SELECTIVE DIELS-ALDER REACTIONS IN AQUEOUS-SOLUTIONS AND SUSPENSIONS [J].

BRESLOW, R ;

MAITRA, U ;

RIDEOUT, D .

TETRAHEDRON LETTERS, 1983, 24 (18) :1901-1904

[5] A novel and efficient synthesis of pyrimido[4,5-d]pyrimidine-2,4,7-trione and pyrido[2,3-d:6,5-d] dipyrimidine-2,4,6,8-tetrone derivatives [J].

Dabiri, Minoo ;

Arvin-Nezhad, Harnid ;

Khavasi, Hamid Reza ;

Bazgir, Ayoob .

TETRAHEDRON, 2007, 63 (08) :1770-1774

[6] Studies on uracils:: a facile one-pot synthesis of oxazino[4,5-d]-, pyrano[2,3-d]-, pyrido[2,3-d]- and pyrimido[4,5-d]pyrimidines using microwave irradiation in the solid state [J].

Devi, I ;

Borah, HN ;

Bhuyan, PJ .

TETRAHEDRON LETTERS, 2004, 45 (11) :2405-2408

[7]

El-Moghazy Samir M, 2011, Sci Pharm, V79, P429, DOI 10.3797/scipharm.1103-16

[8]

Ghorbani-Vaghei R., 2016, APPL ORGANOMETAL CHE

[9] A facile microwave induced one-pot synthesis of novel pyrimido[4,5-d]pyrimidines and pyrido[2,3-d]pyrimidines under solvent-free conditions [J].

Gohain, M ;

Prajapati, D ;

Gogoi, BJ ;

Sandhu, JS .

SYNLETT, 2004, (07) :1179-1182

[10] Fe3O4@Silica sulfuric acid core-shell composite as a novel nanomagnetic solid acid: synthesis, characterization and application as an efficient and reusable catalyst for one-pot synthesis of 3,4-dihydropyrimidinones/thiones under solvent-free conditions [J].

Kiasat, Ali Reza ;

Davarpanah, Jamal .

RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 41 (05) :2991-3001

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