Three new, 1-oxygenated ent-8,9-secokaurane diterpenes from Croton kongensis

被引：15

作者：

Chen, W

Yang, XD

Zhao, JF

Yang, JH

Zhang, HB

Li, ZY ^{[1
]}

Li, L

机构：

[1] Kunming Univ Sci & Technol, Sch Environm Sci & Engn, Kunming 650093, Yunnan, Peoples R China

[2] Yunnan Univ, Res Sch Pharm, Minist Educ, Key Lab Med Chem Nat Resource, Kunming 650091, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2006年 / 89卷 / 03期

关键词：

D O I：

10.1002/hlca.200690057

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three new ent-8,9-secokaurane diterpenes, kongensins A-C (1-3), were isolated from the aerial parts of Croton kongensis, together with two known compounds, rabdoumbrosanin (4) and (7 alpha,14 beta)-7,14-dihydroxy-ent-kaur-16-en-15-one (5). The structures of the new compounds were elucidated by HR-MS as well as in-depth 1D- and 2D-NMR analyses. Compounds 1-3 showed an unusual oxygenation pattern, with an AcO or OH group at C(1), in combination with a Delta(8(14)) unsaturation (1) or an 8,14-epoxide function (2, 3).

引用

页码：537 / 541

页数：5

共 7 条

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