Intermediate filaments and cellular mechanics

被引：36

作者：

Goldmann, Wolfgang H. ^{[1
]}

机构：

[1] Friedrich Alexander Univ Erlangen Nuremberg, Biophys Grp, Dept Phys, D-91052 Erlangen, Germany

来源：

CELL BIOLOGY INTERNATIONAL | 2018年 / 42卷 / 02期

关键词：

cellular mechanics; desmin; filamin C; intermediate filaments; lamin (A; C); plectin; BIOMECHANICAL CHARACTERIZATION; PLECTIN; DESMIN; MUTATION; MUSCLE; DEFECTS; DOMAIN; CARDIOMYOPATHY; ARCHITECTURE; MYOPATHIES;

D O I：

10.1002/cbin.10879

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Intermediate filaments (IFs) are one of the three types of cytoskeletal polymers that resist tensile and compressive forces in cells. They crosslink each other as well as with actin filaments and microtubules by proteins, which include desmin, filamin C, plectin, and lamin (A/C). Mutations in these proteins can lead to a wide range of pathologies, some of which exhibit mechanical failure of the skin, skeletal, or heart muscle.

引用

页码：132 / 138

页数：7

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