Podocytes: Gaining a foothold

被引：33

作者：

Gart, Puneet ^{[3
]}

Holzman, Lawrence B. ^{[1
,2
]}

机构：

[1] Univ Penn, Renal Electrolyte & Hypertens Div, Philadelphia, PA 19104 USA

[2] Dept Vet Affairs, Philadelphia, PA USA

[3] Univ Michigan, Div Nephrol, Ann Arbor, MI 48109 USA

来源：

EXPERIMENTAL CELL RESEARCH | 2012年 / 318卷 / 09期

关键词：

Kidney; Podocyte; Intercellular junction; Cytoskeleton; Glomerulus; FOCAL SEGMENTAL GLOMERULOSCLEROSIS; CONGENITAL NEPHROTIC SYNDROME; TOR SIGNALING NETWORK; ACTIN-BASED MOTILITY; TYROSINE PHOSPHORYLATION; ADHESION KINASE; DIABETIC-NEPHROPATHY; AFRICAN-AMERICANS; POLARITY PROTEIN; SLIT DIAPHRAGMS;

D O I：

10.1016/j.yexcr.2012.02.030

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In an attempt to understand the basis of glomerular disease, significant progress has been made in understanding the mechanisms that determine podocyte development and the maintenance of podocyte health. This review examines recent advances in this area focusing on the podocyte intercellular junction, actin cytoskeletal dynamics, and determinants of podocyte cell polarity, autophagy and mTOR biology. Published by Elsevier Inc.

引用

页码：955 / 963

页数：9