Immune System Network and Cancer Vaccine

被引:49
作者
Bianca, Carlo [1 ]
Pennisi, Marzio [2 ]
Motta, Santo [2 ]
Ragusa, Maria Alessandra [2 ]
机构
[1] Politecn Torino, Dipartimento Matemat, Turin, Italy
[2] Catania Univ, Catania, Italy
来源
NUMERICAL ANALYSIS AND APPLIED MATHEMATICS ICNAAM 2011: INTERNATIONAL CONFERENCE ON NUMERICAL ANALYSIS AND APPLIED MATHEMATICS, VOLS A-C | 2011年 / 1389卷
关键词
Immune System Networks; Biological Network models; Asymptotic Behaviour; IMMUNOPREVENTION;
D O I
10.1063/1.3637764
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
This paper deals with the mathematical modelling of the immune system response to cancer disease, and specifically with the treatment of the mammary carcinoma in presence of an immunoprevenction vaccine. The innate action of the immune system network, the external stimulus represented by repeated vaccine administrations and the competition with cancer are described by an ordinary differential equations-based model. The mathematical model is able to depict preclinical experiments on transgenic mice. The results are of great interest both in the applied and theoretical sciences.
引用
收藏
页码:945 / 948
页数:4
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