"On-water" synthesis of 3-substituted indoles via Knoevenagel/Michael addition sequence catalyzed by Cu doped ZnS NPs

被引：22

作者：

Dandia, Anshu ^{[1
]}

Gupta, Shyam L. ^{[1
]}

Parewa, Vijay ^{[1
]}

Sharma, Amit ^{[1
,2
]}

Rathore, Kuldeep S. ^{[2
]}

Sharma, Amit ^{[1
,2
]}

机构：

[1] Univ Rajasthan, Dept Chem, Ctr Adv Studies, Jaipur 302004, Rajasthan, India

[2] Univ Rajasthan, Dept Phys, Semicond & Polymer Sci Lab, Jaipur 302004, Rajasthan, India

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 42期

关键词：

Copper doped ZnS nanoparticles; Heterogeneous catalyst; On-water synthesis; Indane-1,3-dione; CONJUGATE ADDITION; MICHAEL ADDITION; ORGANIC-REACTIONS; HIGHLY EFFICIENT; AQUEOUS-MEDIA; DISPIRO HETEROCYCLES; DUAL ACTIVATION; CHEMISTRY; CONSTRUCTION; SOLVENT;

D O I：

10.1016/j.tetlet.2013.08.013

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cu doped ZnS NPs represent a green catalyst for an 'on-water' one-pot rapid synthesis of 3-substituted indole derivatives via Knoevenagel/Michael addition reaction of indane-1,3-dione, aromatic aldehydes, and indole. The catalytic activity of Cu doped ZnS NPs was about sevenfold higher as compared to the ZnS NPs. The Cu doped ZnS NPs catalyst could be recovered and reused for five reaction cycles, giving a total TOF = 201 h(-1). (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：5711 / 5717

页数：7

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