CART peptides: regulators of body weight, reward and other functions

被引：253

作者：

Rogge, G. ^{[1
]}

Jones, D. ^{[1
]}

Hubert, G. W. ^{[1
]}

Lin, Y. ^{[1
]}

Kuhar, M. J. ^{[1
]}

机构：

[1] Emory Univ, Yerkes Natl Primate Res Ctr, Div Neurosci, Atlanta, GA 30329 USA

来源：

NATURE REVIEWS NEUROSCIENCE | 2008年 / 9卷 / 10期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrn2493

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Over the past decade or so, CART (cocaine- and amphetamine-regulated transcript) peptides have emerged as major neurotransmitters and hormones. CART peptides are widely distributed in the CNS and are involved in regulating many processes, including food intake and the maintenance of body weight, reward and endocrine functions. Recent studies have produced a wealth of information about the location, regulation, processing and functions of CART peptides, but additional studies aimed at elucidating the physiological effects of the peptides and at characterizing the CART receptor(s) are needed to take advantage of possible therapeutic applications.

引用

页码：747 / 758

页数：12

共 176 条

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