Prevalence and risk factors of human papillomavirus infection by penile site in uncircumcised Kenyan men

被引：39

作者：

Smith, Jennifer S. ^{[1
]}

Backes, Danielle M. ^{[1
]}

Hudgens, Michael G. ^{[2
]}

Bailey, Robert C. ^{[3
]}

Veronesi, Giovanni ^{[4
]}

Bogaarts, Martijn ^{[5
]}

Agot, Kawango ^{[6
]}

Ndinya-Achola, J. O. ^{[7
]}

Maclean, Ian ^{[8
]}

Agingu, Walter ^{[6
]}

Meijer, Chris J. L. M. ^{[5
]}

Moses, Stephen ^{[8
]}

Snijders, Peter J. F. ^{[5
]}

机构：

[1] Univ N Carolina, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Biostat, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27599 USA

[3] Univ Illinois, Chicago, IL USA

[4] Univ Insubria, Dipartimento Sci Clin & Biol, Varese, Italy

[5] Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands

[6] UNIM Project, Kisumu, Kenya

[7] Univ Nairobi, Nairobi, Kenya

[8] Univ Manitoba, Winnipeg, MB R3T 2N2, Canada

来源：

INTERNATIONAL JOURNAL OF CANCER | 2010年 / 126卷 / 02期

基金：

加拿大健康研究院; 美国国家卫生研究院;

关键词：

Human papillomavirus; HPV; Glans; Shaft; Men; Prevalence; Kenya; YOUNG MEN; LESIONS; CANCER; WOMEN;

D O I：

10.1002/ijc.24770

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human papillomavirus (HPV) prevalence was estimated from 2,705 sexually active, uncircumscised human immunodeficiency virus seronegative men aged 17-28 years in Kisumu, Kenya. HPV prevalence was 51.1% (95% confidence interval 49.2-53.00%) in penile cells from the glans/coronal sulcus and/or shaft. HPV prevalence varied by anatomical site with 46.5% positivity in the glans/coronal sulcus compared with 19.1% in the shaft (P < 0.001). High-risk HPV was detected in 31.22% of glans and 12.3% of shaft samples (p < 0.0001). HPV16 was the most common type and 29.2% of men were infected with sexually transmitted infections, and less frequent bathing. Lifetime number of sexual partners and herpes simplex virus type-2 seropositivity were also marginally associated with HPV infection.

引用

页码：572 / 577

页数：6

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