Prevalence and risk factors of human papillomavirus infection by penile site in uncircumcised Kenyan men

被引：39

作者：

Smith, Jennifer S. ^{[1
]}

Backes, Danielle M. ^{[1
]}

Hudgens, Michael G. ^{[2
]}

Bailey, Robert C. ^{[3
]}

Veronesi, Giovanni ^{[4
]}

Bogaarts, Martijn ^{[5
]}

Agot, Kawango ^{[6
]}

Ndinya-Achola, J. O. ^{[7
]}

Maclean, Ian ^{[8
]}

Agingu, Walter ^{[6
]}

Meijer, Chris J. L. M. ^{[5
]}

Moses, Stephen ^{[8
]}

Snijders, Peter J. F. ^{[5
]}

机构：

[1] Univ N Carolina, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Biostat, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27599 USA

[3] Univ Illinois, Chicago, IL USA

[4] Univ Insubria, Dipartimento Sci Clin & Biol, Varese, Italy

[5] Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands

[6] UNIM Project, Kisumu, Kenya

[7] Univ Nairobi, Nairobi, Kenya

[8] Univ Manitoba, Winnipeg, MB R3T 2N2, Canada

来源：

INTERNATIONAL JOURNAL OF CANCER | 2010年 / 126卷 / 02期

基金：

加拿大健康研究院; 美国国家卫生研究院;

关键词：

Human papillomavirus; HPV; Glans; Shaft; Men; Prevalence; Kenya; YOUNG MEN; LESIONS; CANCER; WOMEN;

D O I：

10.1002/ijc.24770

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human papillomavirus (HPV) prevalence was estimated from 2,705 sexually active, uncircumscised human immunodeficiency virus seronegative men aged 17-28 years in Kisumu, Kenya. HPV prevalence was 51.1% (95% confidence interval 49.2-53.00%) in penile cells from the glans/coronal sulcus and/or shaft. HPV prevalence varied by anatomical site with 46.5% positivity in the glans/coronal sulcus compared with 19.1% in the shaft (P < 0.001). High-risk HPV was detected in 31.22% of glans and 12.3% of shaft samples (p < 0.0001). HPV16 was the most common type and 29.2% of men were infected with sexually transmitted infections, and less frequent bathing. Lifetime number of sexual partners and herpes simplex virus type-2 seropositivity were also marginally associated with HPV infection.

引用

页码：572 / 577

页数：6

共 15 条

[1] Systematic review of human papillomavirus prevalence in invasive penile cancer [J].

Backes, Danielle M. ;

Kurman, Robert J. ;

Pimenta, Jeanne M. ;

Smith, Jennifer S. .

CANCER CAUSES & CONTROL, 2009, 20 (04) :449-457

[2] Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial [J].

Bailey, Robert C. ;

Moses, Stephen ;

Parker, Corette B. ;

Agot, Kawango ;

Maclean, Ian ;

Krieger, John N. ;

Williams, Carolyn F. M. ;

Campbell, Richard T. ;

Ninya-Achola, Jeckoniah O. .

LANCET, 2007, 369 (9562) :643-656

[3]

FERLAY J, 2002, IARC CANC BASE, V5

[4] Cervical infection with Chlamydia trachomatis and Neisseria gonorrhoeae in women from ten areas in four continents [J].

Franceschi, Silvia ;

Smith, Jennifer S. ;

Van Den Brule, Adriaan ;

Herrero, Rolando ;

Arslan, Annie ;

Anh, Pham-Thi-Hoang ;

Bosch, F. Xavier ;

Hieu, Nguyen-Trong ;

Matos, Elena ;

Posso, Hector ;

Qiao, You-Lin ;

Shin, Hai-Rim ;

Sukvirach, Sukhon ;

Thomas, Jaiye O. ;

Snijders, Peter J. F. ;

Munoz, Nubia ;

Meijer, Chris J. L. M. .

SEXUALLY TRANSMITTED DISEASES, 2007, 34 (08) :563-569

[5] Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions [J].

Hoots, Brooke E. ;

Palefsky, Joel M. ;

Pimenta, Jeanne M. ;

Smith, Jennifer S. .

INTERNATIONAL JOURNAL OF CANCER, 2009, 124 (10) :2375-2383

[6] Sexual and demographic determinants for herpes simplex virus type 2 among fishermen along Lake Victoria, Kenya [J].

Ng'ayo, M. O. ;

Bukusi, E. ;

Morrow, R. A. ;

Rowhani-Rahbar, A. ;

Obare, B. A. ;

Friedrich, D. ;

Holmes, K. K. .

SEXUALLY TRANSMITTED INFECTIONS, 2008, 84 (02) :140-142

[7] Risk factors for anogenital human papillomavirus infection in men [J].

Nielson, Carrie M. ;

Harris, Robin B. ;

Dunne, Eileen F. ;

Abrahamsen, Martha ;

Papenfuss, Mary R. ;

Flores, Roberto ;

Markowitz, Lauri E. ;

Giuliano, Anna R. .

JOURNAL OF INFECTIOUS DISEASES, 2007, 196 (08) :1137-1145

[8] Human papillomavirus prevalence and type distribution in male anogenital sites and semen [J].

Nielson, Carrie M. ;

Flores, Roberto ;

Harris, Robin B. ;

Abrahamsen, Martha ;

PapenfuSS, Mary R. ;

Dunne, Eileen F. ;

Markowitz, Lauri E. ;

Giuliano, Anna R. .

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2007, 16 (06) :1107-1114

[9] Infection with human papiIlomaviruses of sexual partners of women having cervical intraepithelial neoplasia [J].

Rombaldi, RL ;

Serafini, EP ;

Villa, LL ;

Vanni, AC ;

Baréa, F ;

Frassini, R ;

Xavier, M ;

Paesi, S .

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2006, 39 (02) :177-187

[10] Age-Specific Prevalence of Infection with Human Papillomavirus in Females: A Global Review [J].

Smith, Jennifer S. ;

Melendy, Amy ;

Rana, Rashida K. ;

Pimenta, Jeanne M. .

JOURNAL OF ADOLESCENT HEALTH, 2008, 43 (04) :S5-S25

← 1 2 →