In Vitro Activities of Panduratin A against Clinical Staphylococcus Strains

被引：52

作者：

Rukayadi, Yaya ^{[1
,2
,3
]}

Lee, Kwanghyung ^{[4
]}

Han, Sunghwa ^{[4
]}

Yong, Dongeun ^{[5
,6
]}

Hwang, Jae-Kwan ^{[1
,4
]}

机构：

[1] Yonsei Univ, Dept Biotechnol, Seoul 120749, South Korea

[2] Bogor Agr Univ, Biopharmaca Res Ctr, Bogor 16151, Indonesia

[3] Bogor Agr Univ, Res Ctr Biotechnol & Bioresources, Bogor 16151, Indonesia

[4] Yonsei Univ, Dept Biomat Sci & Engn, Seoul 120749, South Korea

[5] Yonsei Univ, Dept Lab Med, Seoul 120749, South Korea

[6] Yonsei Univ, Res Inst Bacterial Resistance, Seoul 120749, South Korea

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 10期

关键词：

ANTIBACTERIAL ACTIVITY; KAEMPFERIA-PANDURATA; MEDICAL PROGRESS; MEDICINAL-PLANTS; AUREUS; INFECTIONS;

D O I：

10.1128/AAC.00624-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In vitro antistaphylococcal activities of panduratin A, a natural chalcone compound isolated from Kaempferia pandurata Roxb, were compared to those of commonly used antimicrobials against clinical staphylococcal isolates. Panduratin A had a MIC at which 90% of bacteria were inhibited of 1 mu g/ml for clinical staphylococcal isolates and generally was more potent than commonly used antimicrobials.

引用

页码：4529 / 4532

页数：4

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