Palladium-catalyzed [3C+2C+2C] cycloaddition of enynylidenecyclopropanes: efficient construction of fused 5-7-5 tricyclic systems

被引：60

作者：

Bhargava, Gaurav ^{[2
]}

Trillo, Beatriz ^{[2
]}

Araya, Marisel ^{[2
]}

Lopez, Fernando ^{[1
]}

Castedo, Luis ^{[2
]}

Mascarenas, Jose L. ^{[2
]}

机构：

[1] CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain

[2] Univ Santiago de Compostela, Dept Quim Organ, Santiago De Compostela 15782, Spain

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 02期

关键词：

3+2 INTRAMOLECULAR CYCLOADDITION; FISCHER CARBENE COMPLEXES; ETHYL CYCLOPROPYLIDENEACETATE; 8-MEMBERED RINGS; ALKYNES; COCYCLIZATION; ALLENES; CO; ALK-5-YNYLIDENECYCLOPROPANES; ALKYLIDENECYCLOPROPANES;

D O I：

10.1039/b919258a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a Pd-catalyzed intramolecular [3C + 2C + 2C] cycloaddition between alkylidenecyclopropanes, alkynes and alkenes. The method provides synthetically relevant 5-7-5 tricyclic structures, with good chemoselectivity and complete diastereoselectivity.

引用

页码：270 / 272

页数：3

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