Oviduct-specific glycoprotein 1 locus is associated with litter size and weight of ovaries in pigs

被引：8

作者：

Niu, BY ^{[1
]}

Xiong, YZ ^{[1
]}

Li, FE ^{[1
]}

Jiang, SW ^{[1
]}

Deng, CY ^{[1
]}

Ding, SH ^{[1
]}

Guo, WH ^{[1
]}

Lei, MG ^{[1
]}

Zheng, R ^{[1
]}

Zuo, B ^{[1
]}

Xu, DQ ^{[1
]}

Li, JL ^{[1
]}

机构：

[1] Huazhong Agr Univ, Minist Agr, Key Lab Pig Genet & Breeding, Wuhan 430070, Peoples R China

来源：

ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES | 2006年 / 19卷 / 05期

关键词：

oviduct-specific glycoprotein 1; litter size; female reproductive tract components; pigs;

D O I：

10.5713/ajas.2006.632

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Oviduct-specific glycoprotein 1 (OVGP1) is implicated in playing a role in fertilization and early embryo development. In this study, we have obtained the sequence-of intron 9 of OVGP1 gene in swine.. Comparative sequencing of Meishan (a native Chinese breed) and Large White pig breeds revealed an A/T substitution at position 943. A PCR-EcoRI-RFLP assay was developed to detect this mutation. Polymorphism analysis in Qingping animals showed that pigs with BB genotype had lower number of piglets born alive (NBA) in multiple parities than pigs with AA (p < 0.05) and AB genotype (p < 0.01). In Large WhitexMeishan (LWxM) F-2 offspring, the weight of both ovaries (OW) of the BB genotype was significantly lighter than that of AB (p = 0.05) and AA (p < 0.01) genotypes. Analysis of the data also revealed that the mutation locus affected these two traits mostly by additive effects. These studies indicated that the polymorphism was associated with NBA and OW in two distinct populations and further investigations in more purebreds or crossbreds are needed to confirm these results.

引用

页码：632 / 637

页数：6

共 33 条

[1] Cloning and characterization of the human oviduct-specific glycoprotein (HuOGP) gene promoter [J].

Agarwal, A ;

Yeung, WSB ;

Lee, KF .

MOLECULAR HUMAN REPRODUCTION, 2002, 8 (02) :167-175

[2]

ANDREWS JK, 2000, MOL REPROD DEV, V63, P242

[3] COMPLEMENTARY DEOXYRIBONUCLEIC-ACID CLONING AND MOLECULAR CHARACTERIZATION OF AN ESTROGEN-DEPENDENT HUMAN OVIDUCTAL GLYCOPROTEIN [J].

ARIAS, EB ;

VERHAGE, HG ;

JAFFE, RC .

BIOLOGY OF REPRODUCTION, 1994, 51 (04) :685-694

[4]

Bhatt Purvi, 2004, Indian Journal of Experimental Biology, V42, P1043

[5]

Boatman Dorothy E., 1997, Human Reproduction (Oxford), V12, P133

[6] The effects of estrogen receptor locus on reproductive tracts components and performance traits in large White x Meishan F2 offspring [J].

Fenge, L ;

Lei, MG ;

Zheng, R ;

Zuo, B ;

Jiang, SW ;

Deng, CY ;

Xiong, YZ .

ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 2004, 17 (09) :1223-1226

[7]

Legault C., 1996, Journees de la Recherche Porcine en France, V28, P9

[8]

Li F, 2002, ASIAN AUSTRAL J ANIM, V15, P179

[9]

LIN H, 1992, PORCINE DISSECTION M, P158

[10]

Liu B., 1998, Statistical genomics: linkage, mapping and QTL analysis

← 1 2 3 4 →