THE EFFECT OF THE MIXING RATE OF THE REACTION MIXTURE ON THE DISPERSED CHARACTERISTICS OF THE NANOEMULSION OF FAT-SOLUBLE VITAMIN E (ALPHA-TOCOPHEROL ACETATE)

被引：0

作者：

Blinov, A., V ^{[1
]}

Slyadneva, K. S. ^{[1
]}

Gvozdenko, A. A. ^{[1
]}

Golik, A. B. ^{[1
]}

Taravanov, M. A. ^{[1
]}

Nazaretova, E. D. ^{[2
]}

机构：

[1] North Caucasian Fed Univ, Dept Phys & Technol Nanostruct & Mat, Fac Phys & Technol, Stavropol, Russia

[2] North Caucasian Fed Univ, Specialized Educ & Sci Ctr, Stavropol, Russia

来源：

PHYSICAL AND CHEMICAL ASPECTS OF THE STUDY OF CLUSTERS NANOSTRUCTURES AND NANOMATERIALS | 2022年 / 14期

关键词：

fat-soluble vitamin E; nanoemulsion; hydrodynamic radius; mixing speed; NANO-EMULSIONS; EMULSIFICATION METHODS; STABILIZATION; FORMULATION;

D O I：

10.26456/pcascnn/2022.14.754

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The article presents the results of a study of the effect of the mixing rate on the dispersed characteristics of nanoemulsions of the fat-soluble vitamin E (alpha-tocopherol acetate). The mixing speed was varied in the range of 3000-22500 rpm. The average hydrodynamic radius of the micelles of fat-soluble vitamin E was considered as an output parameter, which was determined by the method of the dynamic light scattering. It was found that as a result of synthesis, micelles of the fat-soluble vitamin E emulsions are formed, having a monomodal size distribution. The smallest average hydrodynamic radius of the particles was 22 nm. It was found that an increase in the mixing speed from 3000 to 22500 rpm causes a decrease in the average hydrodynamic radius of micelles. The greatest changes are observed at tau = 30 s: a decrease in the average hydrodynamic radius of micelles R-m occurs by 3,3 times (from 210 to 63 nm). It is important to note that an increase in other synthesis parameters also leads to a decrease in the value of the average hydrodynamic radius of micelles of the vitamin E nanoemulsions. By v = 22500 rpm an increase in the mixing time tau from 30 s to 270 s leads to a decrease in R-m by 19 nm (from 63 to 44 nm).

引用

页码：754 / 762

页数：9

共 2 条

[1] EFFECT OF IONIC STRENGTH AND ACTIVE ACIDITY OF THE MEDIUM ON THE STABILITY OF VITAMIN E NANOEMULSIONS (ALPHA-TOCOPHEROL ACETATE)
Nagdalian, A. A.
Blinov, A. V.
Golik, A. B.
Blinova, A. A.
Gvozdenko, A. A.
Maglakelidze, D. G.
IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA I KHIMICHESKAYA TEKHNOLOGIYA, 2022, 65 (12): : 24 - 29
[2] STUDY OF THE INFLUENCE OF SYNTHESIS PARAMETERS ON THE AVERAGE HYDRODYNAMIC RADIUS OF VITAMIN E (ALPHA-TOCOPHEROL ACETATE) MICELLES
Blinov, A., V
Nagdalyan, A. A.
Gvozdenko, A. A.
Golik, A. B.
Slyadrieva, K. S.
Pirogov, M. A.
IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA I KHIMICHESKAYA TEKHNOLOGIYA, 2022, 65 (07): : 45 - 53

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