Successful treatment of severe thrombocytopenia with romiplostim in a pregnant patient with systemic lupus erythematosus

被引：47

作者：

Alkaabi, J. K. ^{[1
]}

Alkindi, S. ^{[2
]}

Al Riyami, N. ^{[3
]}

Zia, F. ^{[2
]}

Balla, L. M. A. ^{[1
]}

Balla, S. M. ^{[3
]}

机构：

[1] Sultan Qaboos Univ Hosp, Dept Med, Rheumatol Unit, Muscat 123, Oman

[2] Sultan Qaboos Univ Hosp, Dept Haematol, Muscat 123, Oman

[3] Sultan Qaboos Univ Hosp, Dept Obstet & Gynecol, Muscat 123, Oman

来源：

LUPUS | 2012年 / 21卷 / 14期

关键词：

Antiphospholipid syndrome; Evans syndrome; rituximab; eltrombopag; romiplostim; systemic lupus erythematosus; thrombocytopenia; EFFICACY;

D O I：

10.1177/0961203312463621

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a case of a pregnant woman at 27 weeks of gestation with systemic lupus erythematosus who developed severe thrombocytopenia presenting with melena, epistaxis, gum bleeding and frank hematuria. She was resistant to most treatment modalities, including steroids, intravenous immunoglobulins (IVIG), rituximab, IV cyclophosphamide and eltrombopag. She responded to romiplostim with normalization of her platelet count, which enabled her to be delivered safely at 34 weeks of gestation. Lupus (2012) 21, 1571-1574.

引用

页码：1571 / 1574

页数：4

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