Two new triterpenes from the husks of Xanthoceras sorbifolia

被引：36
作者：
Li, ZL
Li, X
Li, LH
Li, N
Yu, M
Meng, DL
机构：
[1] Shenyang Pharmaceut Univ, Res Dept Nat Med, Shenyang 110016, Peoples R China
[2] Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Peoples R China
来源：
PLANTA MEDICA | 2005年 / 71卷 / 11期
关键词：
D O I：
10.1055/s-2005-873108
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new triterpenes, 22-angeloyl-21-epoxyangeloylbarringtogenol C (1) and 21,22-diangeloyl-24-hydroxy-Rl-barrigenoI (2), and the known 21,22-diangeloyl-R-1-barrigenol (3) were isolated from the husks of Xanthoceras sorbifolia Bunge. Their structures were elucidated based on detailed NMR analysis. Compounds 1 and 2 inhibited significantly the growth of cancer cell lines (A375-S2, HeLa) with IC50 values ranging from 2.9 to 76.3 mu mol/L.
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页码：1068 / 1070
页数：3
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